Protein Alignment Klp59D and Klp68D

DIOPT Version :10

• Sequence 1: NP_611762.1
• Gene: Klp59D / 37674
• FlyBaseID: FBgn0034827
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Alignment Length: 614
• Identity: 176/614 - (28%)
• Similarity: 267/614 - (43%)
• Gaps: 130/614 - (21%)

  Fly   226 PNGGTVQQ----ITVCVRKRPMSRKEENSKNLDIITV-PSADSLIVHELRLKVDLTKFLEHHK-F 284
            |..|:.|.    :.|.||.||||.:|.:.::.:::.| |:..   |.||:..||..|  |..| |
  Fly     8 PGTGSSQTPNECVQVVVRCRPMSNRERSERSPEVVNVYPNRG---VVELQNVVDGNK--EQRKVF 67

  Fly   285 RFDYTFDEECSNALVYDHTARPLIRTMFEGGNATCFAYGQTGSGKTHTMGGEFFGKVQDCGTGIY 349
            .:|..:|...:...:|.....||:.::.||.|...|||||||:|||.||.|.   :..|...||.
  Fly    68 TYDAAYDASATQTTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGV---RGNDELMGII 129

  Fly   350 AMAARDVFEEVSRPEYRQMGAKITCSFFEIYGTKVFDLLLPNKPMLRVLEDARQQVVVVGLTEMP 414
            ......::..::|.|..|.  .:..|:.|||..::.|||.||...|.|.|.. ..|.|..|..:.
  Fly   130 PRTFEQIWLHINRTENFQF--LVDVSYLEIYMEELRDLLKPNSKHLEVRERG-SGVYVPNLHAIN 191

  Fly   415 VTKVEDVLRLIEHGSKERTSGQTSANAKSSRSHAVFQIALHFPDSWG---PHGKCSFVDLAGNER 476
            ...|||::::::.|:|.||.|.|:.|..||||||:|.|.:...|:..   ..||.:.:||||:||
  Fly   192 CKSVEDMIKVMQVGNKNRTVGFTNMNEHSSRSHAIFMIKIEMCDTETNTIKVGKLNLIDLAGSER 256

  Fly   477 GADT-QSADRQTRIEGAEINKSLLALKECIRALSRQSSHLPFRGSKLTQVLRDSFVGGKKNKTCM 540
            .:.| .||:|..  |.::||.:|.:|...|.||:..|.|:|:|.||||::|:||.  |..:||.|
  Fly   257 QSKTGASAERLK--EASKINLALSSLGNVISALAESSPHVPYRDSKLTRLLQDSL--GGNSKTIM 317

  Fly   541 IAMISPSMSCVENTLNTLRYADRVKEL----IAKEDEH---LQSVEGDGEK-----SPDLNEESE 593
            ||.|.||......||.|||||.|.|.:    |..||..   |:..:.:.|:     .|...:.||
  Fly   318 IANIGPSNYNYNETLTTLRYASRAKSIQNQPIKNEDPQDAKLKEYQEEIERLKRLIGPQQQQRSE 382

  Fly   594 PEMMA----------------------------------DEEGDEEPEDEDNQHLTISSEEASSY 624
            .::.|                                  |.||.|...|::|:     :|.|.|.
  Fly   383 KQVTAKKQRVKKPKKETVTKEMSDSLQVSTIEQPVEDDSDPEGAESESDKENE-----AEVAKSN 442

  Fly   625 NNMSYDMSFNHTL----------------NILG--PSRNVDIQ----EVAE--------QHALLV 659
            ..:..:...|..|                |:|.  ..|.::::    |:||        |..|.:
  Fly   443 EELERERVENSKLAAKLAELEGQLVRGGKNLLDTYSERQIELEKKLVEIAERKKREIEIQQQLEL 507

  Fly   660 ENLETYAHNFRQLKTDKEIEQYTQNSESALMKLLAMVNRTRDV--THNYNTQKLLKEEN------ 716
            :...|.....|.:..::|:|...:.......|.||:.....|.  .||.:.::|...:|
  Fly   508 QEETTLEIRERNVSLEQEVELKKRKLSKCYAKYLALQQELNDCKSDHNQDLRELEMAQNELVKEL 572

  Fly   717 ----------------QNAYKKGELDESE 729
                            |..|.:.:.||.:
  Fly   573 KRQLLIIDNFVPIEVKQRLYTQAKYDEEQ 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59D	NP_611762.1	KISc_KIF2_like	233..565	CDD:276818	128/341 (38%)
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	130/345 (38%)
		Smc	<431..>580	CDD:440809	27/153 (18%)