Protein Alignment Klp59D and Klp67A

DIOPT Version :10

• Sequence 1: NP_611762.1
• Gene: Klp59D / 37674
• FlyBaseID: FBgn0034827
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_523992.2
• Gene: Klp67A / 39068
• FlyBaseID: FBgn0004379
• Length: 814
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 152/540 - (28%)
• Similarity: 250/540 - (46%)
• Gaps: 87/540 - (16%)

  Fly   234 ITVCVRKRPMSRKEENSKNLDIITVPSADSLIV---------------HELRLKVDLTKFLEHH- 282
            |.|.||.||.:.:|...|...||.|....:|:.               ...|   |:||.:...
  Fly     9 IKVAVRVRPYNVRELEQKQRSIIKVMDRSALLFDPDEEDDEFFFQGAKQPYR---DITKRMNKKL 70

  Fly   283 KFRFDYTFDEECSNALVYDHTARPLIRTMFEGGNATCFAYGQTGSGKTHTMGGEFFGKVQDCGTG 347
            ...||..||.:.||..:::....||:..:..|.|.:.|.||.||:|||.||.|      .:...|
  Fly    71 TMEFDRVFDIDNSNQDLFEECTAPLVDAVLNGYNCSVFVYGATGAGKTFTMLG------SEAHPG 129

  Fly   348 IYAMAARDVFEEV-SRPEYRQMGAKITCSFFEIYGTKVFDLLLPNKPMLRVLEDARQQVVVVGLT 411
            :..:..:|:|::: ::.:.|:....:  |:.|:|...|.:||..:.| |::.|| ...|||.||.
  Fly   130 LTYLTMQDLFDKIQAQSDVRKFDVGV--SYLEVYNEHVMNLLTKSGP-LKLRED-NNGVVVSGLC 190

  Fly   412 EMPVTKVEDVLRLIEHGSKERTSGQTSANAKSSRSHAVFQIALHFPD---SWGPHGKCSFVDLAG 473
            ..|:...|::||::..|:..||...|.|||:||||||:||:.:...:   ......|.|.:||||
  Fly   191 LTPIYSAEELLRMLMLGNSHRTQHPTDANAESSRSHAIFQVHIRITERKTDTKRTVKLSMIDLAG 255

  Fly   474 NERGADTQSADRQTRIEGAEINKSLLALKECIRALSRQSSHLPFRGSKLTQVLRDSFVGGKKNKT 538
            :||.|.|:....:.: |||.||||||||..||..|:....|:|:|.|.||::|:||.  |...:|
  Fly   256 SERAASTKGIGVRFK-EGASINKSLLALGNCINKLADGLKHIPYRDSNLTRILKDSL--GGNCRT 317

  Fly   539 CMIAMISPSMSCVENTLNTLRYADRVKEL------------------IAKEDEHLQSVEGDGEKS 585
            .|:|.:|.|....|:|.|||:||.|.|::                  :.|.||    |..:.|:.
  Fly   318 LMVANVSMSSLTYEDTYNTLKYASRAKKIRTTLKQNVLKSKMPTEFYVKKIDE----VVAENERL 378

  Fly   586 PDLNEESEPEMMADEEGDE---EPEDEDNQHLTISSEEASSYNNMSYDMSFNHTLNILGPSRNVD 647
            .:.|:..|.:....|....   :|.:....:..|.:..|::....      .|.|.:....:|::
  Fly   379 KERNKALEAKATQLERAGNSGFDPLELKTWYSKIDAVYAAARQLQ------EHVLGMRSKIKNIN 437

  Fly   648 I-----QEVAEQHALLVENLETYAHNFRQLKT-----DKEIEQYTQNSESALMKLLAMVNRTRDV 702
            .     :|:.|...|:..:......:||:...     ..::|:|.:...|.|.|:        ::
  Fly   438 YRQTLKKELEEFRKLMCVDQRVCQEDFRRFANYMSTLTSQMEKYKEELPSWLSKM--------EI 494

  Fly   703 THNYNTQKLLKEENQN-AYK 721
            .:. :.:.|.:|.|:: ||:
  Fly   495 AYQ-DLESLKREVNKSKAYQ 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59D	NP_611762.1	KISc_KIF2_like	233..565	CDD:276818	122/350 (35%)
Klp67A	NP_523992.2	KISc_KIP3_like	8..346	CDD:276821	123/352 (35%)