Protein Alignment Klp59D and Khc

DIOPT Version :10

• Sequence 1: NP_611762.1
• Gene: Klp59D / 37674
• FlyBaseID: FBgn0034827
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Alignment Length: 537
• Identity: 160/537 - (29%)
• Similarity: 244/537 - (45%)
• Gaps: 72/537 - (13%)

  Fly   234 ITVCVRKRPMSRKEENSKNLDIITVPSADSLIVHELRLKVDLTKFLEHHKFRFDYTFDEECSNAL 298
            |.|..|.||::..||.:.:..::..|:.    |.|..:.:....:|      ||..|....|...
  Fly    13 IKVVCRFRPLNDSEEKAGSKFVVKFPNN----VEENCISIAGKVYL------FDKVFKPNASQEK 67

  Fly   299 VYDHTARPLIRTMFEGGNATCFAYGQTGSGKTHTMGGEFFGKVQDCGTGIYAMAARDVFEEVSRP 363
            ||:..|:.::..:..|.|.|.||||||.|||||||.|.....|:.   ||......|:|..:...
  Fly    68 VYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQ---GIIPRIVNDIFNHIYAM 129

  Fly   364 EYRQMGAKITCSFFEIYGTKVFDLLLPNKPMLRVLEDARQQVVVVGLTEMPVTKVEDVLRLIEHG 428
            |. .:...|..|::|||..|:.|||..:|..|.|.||..:...|.|.||..|:..|||..:||.|
  Fly   130 EV-NLEFHIKVSYYEIYMDKIRDLLDVSKVNLSVHEDKNRVPYVKGATERFVSSPEDVFEVIEEG 193

  Fly   429 SKERTSGQTSANAKSSRSHAVFQIAL---HFPDSWGPHGKCSFVDLAGNERGADTQSADRQTRIE 490
            ...|....|:.|..|||||:||.|.:   :..:.....||...|||||:|:.:.| .|:.....|
  Fly   194 KSNRHIAVTNMNEHSSRSHSVFLINVKQENLENQKKLSGKLYLVDLAGSEKVSKT-GAEGTVLDE 257

  Fly   491 GAEINKSLLALKECIRALS-RQSSHLPFRGSKLTQVLRDSFVGGKKNKTCMIAMISPSMSCVENT 554
            ...|||||.||...|.||: ...:|:|:|.||||::|::| :||.. :|.::...||:......|
  Fly   258 AKNINKSLSALGNVISALADGNKTHIPYRDSKLTRILQES-LGGNA-RTTIVICCSPASFNESET 320

  Fly   555 LNTLRYADRVK----------ELIAKEDEHLQSVEGDGEKSPDLN---EESEPEM---------M 597
            .:||.:..|.|          ||.|  :|..:..|.:.||:..|.   |:.|.|:         .
  Fly   321 KSTLDFGRRAKTVKNVVCVNEELTA--EEWKRRYEKEKEKNARLKGKVEKLEIELARWRAGETVK 383

  Fly   598 ADEEGDEE-------PEDEDNQHLTISSEEA-----SSYNNMSYDMSFNHTLNILGPSRNV---- 646
            |:|:.:.|       |..|.....|.::|.|     ::..|||..::.|....:......:
  Fly   384 AEEQINMEDLMEASTPNLEVEAAQTAAAEAALAAQRTALANMSASVAVNEQARLATECERLYQQL 448

  Fly   647 -DIQEVAEQHALLVENL--------ETYAHNFRQLKT-DKEIEQYTQNSESALMKLLAMVNRTRD 701
             |..|...|.:...|.|        |..|:..|:.:| ..|:.:..|.:|||..::..::....:
  Fly   449 DDKDEEINQQSQYAEQLKEQVMEQEELIANARREYETLQSEMARIQQENESAKEEVKEVLQALEE 513

  Fly   702 VTHNYNTQKLLKEENQN 718
            :..||: ||..:.:|:|
  Fly   514 LAVNYD-QKSQEIDNKN 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59D	NP_611762.1	KISc_KIF2_like	233..565	CDD:276818	116/334 (35%)
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	117/336 (35%)
		Smc	<341..>807	CDD:440809	43/192 (22%)
		Khc_CBD_cc	856..925	CDD:467880