Protein Alignment Klp59D and neb

DIOPT Version :9

• Sequence 1: NP_611762.1
• Gene: Klp59D / 37674
• FlyBaseID: FBgn0034827
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Alignment Length: 783
• Identity: 192/783 - (24%)
• Similarity: 291/783 - (37%)
• Gaps: 265/783 - (33%)

  Fly    63 AENQPPISKPPSSLLPKPRGSSPTGGPKTHTGNPYAERMRVQDGRSKIATRKTDPAAVGAGNHEL 127
            ||::....:|...|.....||:|...||                          |.|:.|
  Fly    38 AEDREHRDRPEQLLNTAFSGSTPQPKPK--------------------------PTALNA----- 71

  Fly   128 GRAHTPRVPAGRPDRDASPTQGR-KSQGGNNSNQRFSSVVREVNRMKEQREKRRARQAEQLQEKD 191
              .:||    ....|:|:.|.|| |:.|...|:                        ..:.:|:|
  Fly    72 --CYTP----SSLYRNANSTPGRAKTPGTGKSS------------------------CSRTKERD 106

  Fly   192 ALRR---NNPGNPNWEVSVMLRQYRSTLIFSPLRCLDPNGGTVQQITVCVRKRPMSRKEENSKNL 253
            :|..   :.....|..|:|.:|         ||..|:...|.|..:.         :...||..|
  Fly   107 SLMESCLSVSEESNMIVAVRVR---------PLNALECTRGQVTNVV---------QVHGNSNEL 153

  Fly   254 DIITVPSADSLIVHELRLKVDLTKFLEHHKFRFD---YTFDEECSN----ALVYDHTARPLIRTM 311
            .:....|||:        ...:|     |.|.:|   |:.|.|..|    |.|::.||||||.|.
  Fly   154 TVQAGSSADA--------SAGVT-----HFFSYDQVYYSCDPERKNFACQAKVFEGTARPLIDTA 205

  Fly   312 FEGGNATCFAYGQTGSGKTHTMGGEFFGKVQDCG---------TGIYAMAARDVFEEVSR-PEYR 366
            |||.||..||||||||||:::|.|  ...:.|..         .||......::|..:.. ...:
  Fly   206 FEGYNACLFAYGQTGSGKSYSMMG--IEALDDAALDGGPPHDEAGIIPRFCHELFRRIEAVKSQQ 268

  Fly   367 QMGAKITCSFFEIYGTKVFDLL-------------------LPNKPMLRVLEDARQQVVVVGLTE 412
            |:..::..|:||||..|:.|||                   ...:|.|:|.|.......||.|:.
  Fly   269 QLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQQQQRPALKVREHPIFGPYVVDLSA 333

  Fly   413 MPVTKVEDVLRLIEHGSKERTSGQTSANAKSSRSHAVFQIALHFPDSWGPHG------------- 464
            ..|.....:...:..|:.:|.:..|:.|.||||||::|.|.|:..|.....|
  Fly   334 HSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIVLNLTDLSSDDGLSSDTDSSTASSL 398

  Fly   465 ------KCSFVDLAGNERGADTQSADRQTRIEGAEINKSLLALKECIRAL--SRQ---------- 511
                  |.|.|||||:||.:.:.|...:.| ||..||||||.|.:.|.||  ||:
  Fly   399 RQTRRSKISLVDLAGSERISVSGSNGERIR-EGVSINKSLLTLGKVIAALADSRKAIANGPLGSG 462

  Fly   512 --SSHLPFRGSKLTQVLRDSFVGGKKNKTCMIAMISPSMSCVENTLNTLRYADRVKELIAK---- 570
              |:.:|:|.|.||.:||::.  |..:||.|:|.|||:....:.||.|||||.:.:.::.:
  Fly   463 TPSTFVPYRESVLTWLLRENL--GGNSKTVMLATISPASIHADETLATLRYACKARSIVNRVKVN 525

  Fly   571 -------------EDEHLQSVEGDGEKSPDLN-----------------EESEPE----MMADEE 601
                         |.:.|:|:..:.|:...|:                 :|:|.|    .:|:.|
  Fly   526 ESPHDKIIRDLRAEVDRLKSLRNEYERQRRLSGNSNNPVPRKIIIETSVDETEVEALRQQLAERE 590

  Fly   602 GD------------EEPEDEDNQHLTI-----------SSEEASSYNNMSYDMSFNHTLNILGPS 643
            .:            :|.||:....|.:           :.::.:...|::.|...:.||..|.|.
  Fly   591 RELSRAQKSWMEKLKEAEDQRKSELRVLKRRGLALELTAEQKQACLVNLTADPILSGTLFYLLPQ 655

  Fly   644 RNVDIQE--------------------VAEQHALL-------------VENLETYAHNFRQLKTD 675
            ..|.|..                    ||.||..:             .|:.|||. |...||..
  Fly   656 GLVRIGRGRLPGGSSSSQPDIVLDGPLVALQHCSIEHERGGKLYVIPGSEDFETYV-NGELLKDR 719

  Fly   676 KEI 678
            :::
  Fly   720 RQL 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59D	NP_611762.1	KISc_KIF2_like	233..565	CDD:276818	125/400 (31%)
		Kinesin	239..566	CDD:278646	125/395 (32%)
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	134/441 (30%)
		KISc	120..525	CDD:214526	134/440 (30%)
		Kinesin_assoc	524..657	CDD:292801	20/132 (15%)
		FHA	634..740	CDD:238017	19/90 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437824
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030