Protein Alignment Klp59D and KIF24

DIOPT Version :9

• Sequence 1: NP_611762.1
• Gene: Klp59D / 37674
• FlyBaseID: FBgn0034827
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: XP_011516163.1
• Gene: KIF24 / 347240
• HGNCID: 19916
• Length: 1399
• Species: Homo sapiens
• Alignment Length: 572
• Identity: 220/572 - (38%)
• Similarity: 305/572 - (53%)
• Gaps: 89/572 - (15%)

  Fly   101 MRVQDGRSKIATRKTDPAAVGAGNHELGRAHTPR------VPAGRPDRDASPTQGRK--SQGGNN 157
            |:.:|....|..|....:::...:.||...  ||      .||...||:|| ..|.:  |....:
Human    95 MQEEDKAVSIPERHLQTSSLRIKSQELRSG--PRRQLNFDSPADNKDRNAS-NDGFEMCSLSDFS 156

  Fly   158 SNQRFSSVVREVNRMKEQREKRRARQAEQLQEKDALRRNNPGNPNWEVSVMLRQYRSTLIFS--- 219
            :|::.|:.::.:..|        .....|...|..:.....|:...:..:      ||.:||
Human   157 ANEQKSTYLKVLEHM--------LPDDSQYHTKTGILNATAGDSYVQTEI------STSLFSPNY 207

  Fly   220 --------------------------PLRCLDPNGG-------TVQQITVCVRKRPMSRKEENSK 251
                                      |..|:..|..       .:::|.|||||||:..:|....
Human   208 LSAILGDCDIPIIQRISHVSGYNYGIPHSCIRQNTSEKQNPWTEMEKIRVCVRKRPLGMREVRRG 272

  Fly   252 NLDIITVPSADSLIVHELRLKVDLTKFLEHHKFRFDYTFDEECSNALVYDHTARPLIRTMFEGGN 316
            .::||||...::|:|||.:..||||:::..|.|.||..|.|.|:|..||..|..|||:.:|.|||
Human   273 EINIITVEDKETLLVHEKKEAVDLTQYILQHVFYFDEVFGEACTNQDVYMKTTHPLIQHIFNGGN 337

  Fly   317 ATCFAYGQTGSGKTHTMGGEFFGKVQDCGT----GIYAMAARDVFE--EVSRPEYRQMGAKITCS 375
            ||||||||||:|||:||          .||    |:||:||:|:|.  |||:|.....   :..|
Human   338 ATCFAYGQTGAGKTYTM----------IGTHENPGLYALAAKDIFRQLEVSQPRKHLF---VWIS 389

  Fly   376 FFEIYGTKVFDLLLPNKPMLRVLEDARQQVVVVGLTEMPVTKVEDVLRLIEHGSKERTSGQTSAN 440
            |:|||..:::|||...| .|...||::..|.:|||.|:.|..||.:|.:|..|||||::|.|..|
Human   390 FYEIYCGQLYDLLNRRK-RLFAREDSKHMVQIVGLQELQVDSVELLLEVILKGSKERSTGATGVN 453

  Fly   441 AKSSRSHAVFQIALHFPDSWGPHGKCSFVDLAGNERGADTQSADRQTRIEGAEINKSLLALKECI 505
            |.|||||||.||.:. ..:....|:.||:||||:||.||.:.:||||::||||||:|||||||||
Human   454 ADSSRSHAVIQIQIK-DSAKRTFGRISFIDLAGSERAADARDSDRQTKMEGAEINQSLLALKECI 517

  Fly   506 RALSRQSSHLPFRGSKLTQVLRDSFVGGKKNKTCMIAMISPSMSCVENTLNTLRYADRVKELIAK 570
            |||.::.:|.|||.|||||||:|||:|..  ||||||.||||....|:|||||||||||||| .|
Human   518 RALDQEHTHTPFRQSKLTQVLKDSFIGNA--KTCMIANISPSHVATEHTLNTLRYADRVKEL-KK 579

  Fly   571 EDEHLQSVEG----DGEKSPDLNEESEPEMMADEEGDEEPEDEDNQHLTISS 618
            ..:...||..    .|..||...:.|...:..|:...::.:....|.||:::
Human   580 GIKCCTSVTSRNRTSGNSSPKRIQSSPGALSEDKCSPKKVKLGFQQSLTVAA 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59D	NP_611762.1	KISc_KIF2_like	233..565	CDD:276818	176/337 (52%)
		Kinesin	239..566	CDD:278646	173/332 (52%)
KIF24	XP_011516163.1	SAM_KIF24-like	34..93	CDD:188940
		KISc_KIF2_like	254..575	CDD:276818	176/337 (52%)
		Kinesin	260..576	CDD:278646	173/332 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140814
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D202066at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850