DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Klp59D and Kif24

DIOPT Version :9

Sequence 1:	NP_611762.1	Gene:	Klp59D / 37674	FlyBaseID:	FBgn0034827	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	XP_006238175.1	Gene:	Kif24 / 313170	RGDID:	1307723	Length:	1368	Species:	Rattus norvegicus

Alignment Length:	337	Identity:	179/337 - (53%)
Similarity:	236/337 - (70%)	Gaps:	11/337 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 VQQITVCVRKRPMSRKEENSKNLDIITVPSADSLIVHELRLKVDLTKFLEHHKFRFDYTFDEECS 295
            :::|.|||||||:..:|.....::||||...::|:|||.:..||||:::..|.|.||..|.|.||
  Rat   231 MEKIRVCVRKRPLGVREVRRGEVNIITVEDKETLLVHEKKEAVDLTQYILQHVFYFDEVFGEACS 295

  Fly   296 NALVYDHTARPLIRTMFEGGNATCFAYGQTGSGKTHTMGGEFFGKVQDCGTGIYAMAARDVFEEV 360
            |..||..||.|||:.:|.|||||||||||||:|||:||    .|..|:  .|:||:||:|:|.::
  Rat   296 NQDVYLKTAHPLIQHIFSGGNATCFAYGQTGAGKTYTM----IGTHQN--PGLYALAAKDIFRQL 354

  Fly   361 SRPEYRQMGAKITCSFFEIYGTKVFDLLLPNKPMLRVLEDARQQVVVVGLTEMPVTKVEDVLRLI 425
            ...:.|: ...:..||:|||..:::|||...| .|...||::..|.:.||.|:.|..||.:|::|
  Rat   355 KISQSRR-NLFVWISFYEIYCGQLYDLLNRRK-RLFAREDSKHVVQIAGLRELQVDSVELLLQVI 417

  Fly   426 EHGSKERTSGQTSANAKSSRSHAVFQIALHFPDSWGPHGKCSFVDLAGNERGADTQSADRQTRIE 490
            ..|||||::|.||.||.|||||||.||.:. ..:....|:.||:||||:||.||.:.:||||::|
  Rat   418 LKGSKERSTGATSVNADSSRSHAVIQIQIK-DSAKRTFGRISFIDLAGSERAADARDSDRQTKME 481

  Fly   491 GAEINKSLLALKECIRALSRQSSHLPFRGSKLTQVLRDSFVGGKKNKTCMIAMISPSMSCVENTL 555
            |||||:||||||||||||.::.:|.|||.|||||||:|||:|..  ||||||.||||....|:||
  Rat   482 GAEINQSLLALKECIRALDQEHTHTPFRQSKLTQVLKDSFIGDA--KTCMIANISPSHIATEHTL 544

  Fly   556 NTLRYADRVKEL 567
            ||||||||||||
  Rat   545 NTLRYADRVKEL 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klp59D	NP_611762.1	KISc_KIF2_like	233..565	CDD:276818	175/331 (53%)
Klp59D	NP_611762.1	Kinesin	239..566	CDD:278646	172/326 (53%)
Kif24	XP_006238175.1	SAM_KIF24-like	3..62	CDD:188940
		KISc_KIF2_like	233..554	CDD:276818	175/331 (53%)
		KISc	234..557	CDD:214526	179/334 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334490
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0246
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D202066at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750