Protein Alignment Klp59D and klp-7

DIOPT Version :10

• Sequence 1: NP_611762.1
• Gene: Klp59D / 37674
• FlyBaseID: FBgn0034827
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_001022677.1
• Gene: klp-7 / 176511
• WormBaseID: WBGene00002219
• Length: 747
• Species: Caenorhabditis elegans
• Alignment Length: 725
• Identity: 286/725 - (39%)
• Similarity: 388/725 - (53%)
• Gaps: 102/725 - (14%)

  Fly     6 IGEQLLFQRSDGRVH-QVVCTAKNLERDSITGEWTEGTVVKGKEVPLSTLIGINHHIFAENQPPI 69
            :|..:..:|||||:| .|:...|:..|..:  ||.|....||||..|..|:.:|..:.|....|.
 Worm    62 VGMHVEIKRSDGRIHGAVIAEVKSNGRFMV--EWYEKGETKGKESSLEELLTLNPSLQAPKPTPP 124

  Fly    70 SKPPSSLLPKPRGSSPTGGPKTHTGNPYAERMRVQDGRSKIATR-KTDPAAVGAGNHELGRAHTP 133
            .:||...|......:...|       .:|:.|.:.|..:.:... ...||...:.|.....|.|.
 Worm   125 PQPPQKTLQASTAVNRQNG-------IHAQSMILDDEDTFLLDHINMIPAKGASANKRPTGAFTQ 182

  Fly   134 RVP---------------AGRPDRDASPTQGRKSQG----------------------------- 154
            .||               |..|..||:|..  ||..
 Worm   183 HVPVRMAPPSEKPLPTRRAPSPKEDAAPAP--KSTRTTAAFKPDLDSTAITVPKHTARRTVVVAP 245

  Fly   155 ----------GNNSNQRFSSVVREVNRMKEQREKRRARQAEQLQEKDALRRNNPGNPNWEVSVML 209
                      .|.::||..|   .|.|:...:...|:...:.:|         |.|.|:..:.|:
 Worm   246 APAPVPAPPIANMTSQRAPS---PVARVPSPKNVPRSYPQQDVQ---------PSNGNFAFAEMI 298

  Fly   210 RQYRSTLIFSPLRCLDPNGGTVQQITVCVRKRPMSRKEENSKNLDIITVPSADSLIVHELRLKVD 274
            |.||:.:.:.||...|  |....:|:|||||||:::||.....:|:||:||.|..|:|:.:.:||
 Worm   299 RNYRAQIDYRPLSMFD--GVNENRISVCVRKRPLNKKELTKAEVDVITIPSRDITILHQPQTRVD 361

  Fly   275 LTKFLEHHKFRFDYTFDEECSNALVYDHTARPLIRTMFEGGNATCFAYGQTGSGKTHTMGGEFFG 339
            |||:|::.||||||:|||..:|.|||..||.||::|:|:.|.|||||||||||||||||||:|.|
 Worm   362 LTKYLDNQKFRFDYSFDEYANNELVYRFTAAPLVKTVFDNGTATCFAYGQTGSGKTHTMGGDFSG 426

  Fly   340 KVQDCGTGIYAMAARDVFEEVSRPEYRQMGAKITCSFFEIYGTKVFDLLLPNKPMLRVLEDARQQ 404
            |.|:...||||:.|||||..:.:|:||:....:.|:||||||||.:| ||.:|..||||||..|:
 Worm   427 KKQNASMGIYALTARDVFRMLEQPQYRRKDLSVHCAFFEIYGTKTYD-LLNDKAELRVLEDKMQK 490

  Fly   405 VVVVGLTEMPVTKVEDVLRLIEHGSKERTSGQTSANAKSSRSHAVFQIALHFPDS-WGPHGKCSF 468
            |.||||.|......:|||.||..|:..||:|.|||||.||||||:|||.|..... |   ||.|.
 Worm   491 VQVVGLKEEQAHNEQDVLELINKGTLVRTAGTTSANANSSRSHAIFQIILRQGKKVW---GKFSL 552

  Fly   469 VDLAGNERGADTQSADRQTRIEGAEINKSLLALKECIRALSRQSSHLPFRGSKLTQVLRDSFVGG 533
            :||||||||.||:..||.||.|||.||.||||||||||.::|.|||:|||.||||.||||||: |
 Worm   553 IDLAGNERGQDTRECDRDTRKEGANINTSLLALKECIRGMARNSSHVPFRQSKLTMVLRDSFI-G 616

  Fly   534 KKNKTCMIAMISPSMSCVENTLNTLRYADRVKELIAKEDEHLQSVEGDGEKSPDLNEESEPEMMA 598
            :|::|.||:||||.:|..::|||||||||||||:         ..:|.||.:|..:||......|
 Worm   617 EKSRTVMISMISPGISSSDHTLNTLRYADRVKEM---------GTDGSGEATPIRDEELFLPPSA 672

  Fly   599 DEEGDEEPED--EDNQHLTISSEEASSYNNMSYDMSFNHTL---NILGPSRNVDIQEVAEQHALL 658
            | :.|||.::  |..:|..::.:...:..:||..:....|:   |....::..:.....:|.|.:
 Worm   673 D-KSDEEYDEMVEKQEHRRVAVDHVRNLKDMSEKIIRETTIVLSNEPSAAQKAECLAKLDQLAQI 736

  Fly   659 VENLETYAHN 668
            |.|......|
 Worm   737 VSNTRVAVEN 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59D	NP_611762.1	KISc_KIF2_like	233..565	CDD:276818	199/332 (60%)
klp-7	NP_001022677.1	PHA03378	<161..299	CDD:223065	26/151 (17%)
		KISc_KIF2_like	320..648	CDD:276818	199/332 (60%)