DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13544 and CG12448

DIOPT Version :9

Sequence 1:	NP_611761.1	Gene:	CG13544 / 37673	FlyBaseID:	FBgn0034826	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	NP_723942.2	Gene:	CG12448 / 34942	FlyBaseID:	FBgn0028857	Length:	352	Species:	Drosophila melanogaster

Alignment Length:	358	Identity:	108/358 - (30%)
Similarity:	182/358 - (50%)	Gaps:	40/358 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 DSRSG---NTES----QIGSSKSSNCRLHLISRTGKLLLDYKQYKAARTIQNNWRKFYFRKYFKD 79
            |..||   ||::    .:.|:.|.:......||....||||||:.||||||.:.|.|..|...|.
  Fly    21 DFSSGSHQNTDNFSDCWLESNSSQDSYFGQSSRLKLALLDYKQFNAARTIQCHVRGFLARSTLKR 85

  Fly    80 LRKAVITIQRWWRGFSVRKNHFRYVENLLQKRVQDHHHRAATKIQALFRGWKSRRTIHDHSKLLR 144
            ...|...|.:|||||.||.:.|.:::.|||:|:..:||..|||||||||||.:|:...|...:..
  Fly    86 QIDAATIISKWWRGFWVRHSKFSFMQQLLQQRIIQYHHDMATKIQALFRGWMTRQYFQDFQGMKS 150

  Fly   145 KQVCAAEDLLNCVAFKLHHLLRTFAIPGVYSLKNSNCMSRVEKLLASLHFRFHNGRVKTQLAKEL 209
            .::...||:|:.:..|:|.:.:...:||:|:|:.|:.:|::|.|.::..:|||||||:..:|.:.
  Fly   151 LRIQYVEDMLSSLYRKVHRMRKEHMLPGIYALRESDLLSKIEDLSSTFGYRFHNGRVRAAIAMKR 215

  Fly   210 ADRGKDTETFKRSNKFSKVPFEGARYWSQCKPKCE----AALKMSKNIERRMYRIIEIYDASQRE 270
            :........|::.|.:||||:.|        |..|    ....:.|.:..|:.|.|.:||.:.|:
  Fly   216 SFINDRRHEFRKGNTYSKVPYPG--------PYIENINDLEFTLPKRMTPRLQRTILVYDKAMRD 272

  Fly   271 AHAALVEKNRAYRKHKGLMQNIKKSAEKSKRDFCGDVIASMRRWKILVDNDLTVDKNIFKNPQ-- 333
            .:...|..|  |...:.:..::.:  |..:..||.|.:..:.:            :|..:|.|
  Fly   273 KNVEKVYMN--YSTKRRMSMHVMR--ENMRNRFCKDFVKRLAK------------RNKTRNAQDR 321

  Fly   334 NLERFVAEISQYANEFENCTCYCRIPVFTEIYC 366
            |::.::.::...|:|:   .|:|:..|..:..|
  Fly   322 NIKYYLDDLLTTADEY---NCFCKPQVKDDSLC 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13544	NP_611761.1	COG5022	<12..>301	CDD:227355	95/289 (33%)
CG12448	NP_723942.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464972
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2CGXK
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0014388
OrthoInspector	1	1.000	-	-		otm47562
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.740