DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Klp59C and AT3G16060

DIOPT Version :9

Sequence 1:	NP_611759.1	Gene:	Klp59C / 37671	FlyBaseID:	FBgn0034824	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_566534.1	Gene:	AT3G16060 / 820851	AraportID:	AT3G16060	Length:	684	Species:	Arabidopsis thaliana

Alignment Length:	499	Identity:	198/499 - (39%)
Similarity:	273/499 - (54%)	Gaps:	65/499 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 DREQGKNEDPGNPNWEVARMIRLQREQMESQRVRSGTTNERINC-HQIMVCVRKRPLRRKELADR 205
            |..:..|:.|...        |:..|.:.:::       ||:|. .:|.|.||||||.:||....
plant   138 DDFEAYNKQPNRS--------RVLAENLAAEK-------ERMNAVAKIKVVVRKRPLNKKESTKN 187

  Fly   206 EQDVVSIPSKHTLVVHEPRKHVNLVKFLENHSFRFDYVFDEECSNATVYEFTARPLIKHIFDGGM 270
            |:|:|...: :.|.|||.:..|:|..::|.|.|.||.|.|||.||..||..|..|::..||....
plant   188 EEDIVDTHA-NCLTVHETKLKVDLTAYVEKHEFVFDAVLDEEVSNDEVYRETVEPVVPLIFQRIK 251

  Fly   271 ATCFAYGQTGSGKTYTMGGQFPGRHQSSMDGIYAMAAKDVFSTLKTVPYNKLNLKVYCSFFEIYG 335
            ||||||||||||||||            |..:...|::|:...:... |.....:::.|||||||
plant   252 ATCFAYGQTGSGKTYT------------MKPLPLKASRDILRLMHHT-YRNQGFQLFVSFFEIYG 303

  Fly   336 TRVFDLLMPGKPQLRVLEDRNQQVQVVGLTQNPVQNTAEVLDLLELGNSVRTSGHTSANSKSSRS 400
            .:::|||...| :|.:.||..|||.:|||.:..|.:|..:::|:|.|::.|::|.|.||.:||||
plant   304 GKLYDLLSERK-KLCMREDGKQQVCIVGLQEYRVSDTDAIMELIERGSATRSTGTTGANEESSRS 367

  Fly   401 HAVFQIVL-RSAAGE-----KLHGKFSLIDLAGNERGADNSSADRQTRLEGSEINKSLLVLKECI 459
            ||:.|:.: :|..|.     :|.||.|.|||||:|||||.:..|:||||||:|||||||.|||||
plant   368 HAILQLAIKKSVEGNQSKPPRLVGKLSFIDLAGSERGADTTDNDKQTRLEGAEINKSLLALKECI 432

  Fly   460 RALGRQSSHLPFRGSKLTQVLRDSFIGGKKVKTCMIAMISPCLHSVEHTLNTLRYADRVKELSVE 524
            |||.....|:||||||||:||||||:|..  :|.||:.|||...|.||||||||||||||.||
plant   433 RALDNDQGHIPFRGSKLTEVLRDSFMGNS--RTVMISCISPSSGSCEHTLNTLRYADRVKSLS-- 493

  Fly   525 SIPSKRMPDANLGSTSMSDIVCQSSTQRL-----FPCASSTSMPGG--GNQAQQHTNTANDLNRS 582
                       .|:.|..|:  .|||..|     .|.:|:...|..  .:..:..|...::.:.|
plant   494 -----------KGNASKKDV--SSSTMNLRESTKIPLSSALPTPSNFDDDVNEMWTEENDEFDAS 545

  Fly   583 QKPTSKPTYPTSGQQLVQRKGSSQREASMMLTKSLAQFRGRNFP 626
            .....|..:..:|:......|.:|..    :.|...|.:.|:.|
plant   546 DYEQDKQMWKKNGKLEPSYNGMAQER----IPKPTIQMKSRDMP 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klp59C	NP_611759.1	KISc_KIF2_like	187..519	CDD:276818	166/337 (49%)
Klp59C	NP_611759.1	Kinesin	193..520	CDD:278646	164/332 (49%)
AT3G16060	NP_566534.1	KISc_KIF2_like	169..490	CDD:276818	166/337 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	319	1.000	Domainoid score	I283
eggNOG	1	0.900	-	-		E2759_KOG0246
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	329	1.000	Inparanoid score	I681
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D418348at2759
OrthoFinder	1	1.000	-	-		FOG0001531
OrthoInspector	1	1.000	-	-		mtm1030
orthoMCL	1	0.900	-	-		OOG6_100492
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X866
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.730