Protein Alignment Klp59C and KIF24

DIOPT Version :9

• Sequence 1: NP_611759.1
• Gene: Klp59C / 37671
• FlyBaseID: FBgn0034824
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: XP_011516163.1
• Gene: KIF24 / 347240
• HGNCID: 19916
• Length: 1399
• Species: Homo sapiens
• Alignment Length: 649
• Identity: 231/649 - (35%)
• Similarity: 330/649 - (50%)
• Gaps: 126/649 - (19%)

  Fly    21 LAEIIKLEGGDSKLITVEWPEGH------TVRGKELPLELVVLMNPHIFDSP------------- 66
            |.:|||:...:.|.:::  ||.|      .::.:||.......:|   ||||
Human    88 LIKIIKIMQEEDKAVSI--PERHLQTSSLRIKSQELRSGPRRQLN---FDSPADNKDRNASNDGF 147

  Fly    67 -RCSGGNAASANQ--------------------------TASISPRSMKQRIATGSLSPVLATAP 104
             .||..: .|||:                          .|:.....::..|:|...||...:|.
Human   148 EMCSLSD-FSANEQKSTYLKVLEHMLPDDSQYHTKTGILNATAGDSYVQTEISTSLFSPNYLSAI 211

  Fly   105 PRQQTAPPVREDEVVHQAERMRKERERRREAQARTRLDREQGKNEDPGNPNWEVARMIRLQREQM 169
            ......|.::                         |:....|.|.  |.|:    ..||    |.
Human   212 LGDCDIPIIQ-------------------------RISHVSGYNY--GIPH----SCIR----QN 241

  Fly   170 ESQRVRSGTTNERINCHQIMVCVRKRPLRRKELADREQDVVSIPSKHTLVVHEPRKHVNLVKFLE 234
            .|::....|..|:|.     ||||||||..:|:...|.:::::..|.||:|||.::.|:|.:::.
Human   242 TSEKQNPWTEMEKIR-----VCVRKRPLGMREVRRGEINIITVEDKETLLVHEKKEAVDLTQYIL 301

  Fly   235 NHSFRFDYVFDEECSNATVYEFTARPLIKHIFDGGMATCFAYGQTGSGKTYTMGGQFPGRHQSSM 299
            .|.|.||.||.|.|:|..||..|..|||:|||:||.||||||||||:||||||    .|.|::
Human   302 QHVFYFDEVFGEACTNQDVYMKTTHPLIQHIFNGGNATCFAYGQTGAGKTYTM----IGTHEN-- 360

  Fly   300 DGIYAMAAKDVFSTLKTVPYNKLNLKVYCSFFEIYGTRVFDLLMPGKPQLRVLEDRNQQVQVVGL 364
            .|:||:||||:|..|: |...:.:|.|:.||:|||..:::|||...| :|...||....||:|||
Human   361 PGLYALAAKDIFRQLE-VSQPRKHLFVWISFYEIYCGQLYDLLNRRK-RLFAREDSKHMVQIVGL 423

  Fly   365 TQNPVQNTAEVLDLLELGNSVRTSGHTSANSKSSRSHAVFQIVLRSAAGEKLHGKFSLIDLAGNE 429
            .:..|.:...:|:::..|:..|::|.|..|:.|||||||.||.::.:| ::..|:.|.|||||:|
Human   424 QELQVDSVELLLEVILKGSKERSTGATGVNADSSRSHAVIQIQIKDSA-KRTFGRISFIDLAGSE 487

  Fly   430 RGADNSSADRQTRLEGSEINKSLLVLKECIRALGRQSSHLPFRGSKLTQVLRDSFIGGKKVKTCM 494
            |.||...:||||::||:|||:|||.||||||||.::.:|.|||.|||||||:|||||  ..||||
Human   488 RAADARDSDRQTKMEGAEINQSLLALKECIRALDQEHTHTPFRQSKLTQVLKDSFIG--NAKTCM 550

  Fly   495 IAMISPCLHSVEHTLNTLRYADRVKELS-----VESIPSKRMPDANLGST-------SMSDIVCQ 547
            ||.|||...:.||||||||||||||||.     ..|:.|:.....|....       ::|:..|.
Human   551 IANISPSHVATEHTLNTLRYADRVKELKKGIKCCTSVTSRNRTSGNSSPKRIQSSPGALSEDKCS 615

  Fly   548 SSTQRLFPCASSTSMPGGGNQAQQHTNTANDLNRSQKPTSKPTYP-TSGQQLVQRKGSSQREAS 610
            ....:|....|.|....|..:.:.|..|::          .|..| ||..::..::|.|:...|
Human   616 PKKVKLGFQQSLTVAAPGSTRGKVHPLTSH----------PPNIPFTSAPKVSGKRGGSRGSPS 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59C	NP_611759.1	KISc_KIF2_like	187..519	CDD:276818	170/331 (51%)
		Kinesin	193..520	CDD:278646	168/326 (52%)
KIF24	XP_011516163.1	SAM_KIF24-like	34..93	CDD:188940	2/4 (50%)
		KISc_KIF2_like	254..575	CDD:276818	171/336 (51%)
		Kinesin	260..576	CDD:278646	168/326 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140812
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D202066at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100492
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750