Protein Alignment Klp59C and Klp10A

DIOPT Version :9

• Sequence 1: NP_611759.1
• Gene: Klp59C / 37671
• FlyBaseID: FBgn0034824
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001285109.1
• Gene: Klp10A / 32049
• FlyBaseID: FBgn0030268
• Length: 805
• Species: Drosophila melanogaster
• Alignment Length: 713
• Identity: 317/713 - (44%)
• Similarity: 399/713 - (55%)
• Gaps: 140/713 - (19%)

  Fly     1 MDKLSIEQKIFIRRSDGRVHLAEIIKLEGGDSKLITVEWPEGHTVRGKELPLELVVLMNPHIF-- 63
            ||.:::.|.:.|:|:|||||:| ::.:.....|.|||||.|....:|||:.|:.::.:||.:.
  Fly     1 MDMITVGQSVKIKRTDGRVHMA-VVAVINQSGKCITVEWYERGETKGKEVELDAILTLNPELMQD 64

  Fly    64 ----------------------------------------------------------------- 63
                                                                             
  Fly    65 TVEQHAAPEPKKQATAPMNLSRNPTQSAIGGNLTSRMTMAGNMLNKIQESQSIPNPIVSSNSVNT 129

  Fly    64 --DSPRCSGGNAASANQTASISPRSMKQRIATGSLSPVLATAPPRQQTAPP-------------- 112
              :|...:||...:...|.:...|....:.|||.....:|:|.|......|
  Fly   130 NSNSNTTAGGGGGTTTSTTTGLQRPRYSQAATGQQQTRIASAVPNNTLPNPSAAASAGPAAQGVA 194

  Fly   113 ------------VREDEVVHQAERMRKERERRREAQARTRLDREQGKNEDPGNPNWEVARMIRLQ 165
                        .|....:.:.||:::.||:||..||..:.::....|:||||||||.|:|||..
  Fly   195 TAATTQGAGGASTRRSHALKEVERLKENREKRRARQAEMKEEKVALMNQDPGNPNWETAQMIREY 259

  Fly   166 REQMESQRVRSGTTNERINCHQIMVCVRKRPLRRKELADREQDVVSIPSKHTLVVHEPRKHVNLV 230
            :..:|...:..|   :.::.|||.|||||||:.|||:..:|.||:|:|.|..|:|||||..|:|.
  Fly   260 QSTLEFVPLLDG---QAVDDHQITVCVRKRPISRKEVNRKEIDVISVPRKDMLIVHEPRSKVDLT 321

  Fly   231 KFLENHSFRFDYVFDEECSNATVYEFTARPLIKHIFDGGMATCFAYGQTGSGKTYTMGGQFPGRH 295
            ||||||.|||||.|::.|.||.||::||:||:|.||:|||||||||||||||||:||||:|.|:.
  Fly   322 KFLENHKFRFDYAFNDTCDNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEFNGKV 386

  Fly   296 QSSMDGIYAMAAKDVFSTLKTVPYNKLNLKVYCSFFEIYGTRVFDLLMPGKPQLRVLEDRNQQVQ 360
            |...:|||||||||||.||....|..:||.|..||||||..:||||| ..|.:||||||..||||
  Fly   387 QDCKNGIYAMAAKDVFVTLNMPRYRAMNLVVSASFFEIYSGKVFDLL-SDKQKLRVLEDGKQQVQ 450

  Fly   361 VVGLTQNPVQNTAEVLDLLELGNSVRTSGHTSANSKSSRSHAVFQIVLRSAAGEKLHGKFSLIDL 425
            |||||:..|....|||.|::.||:.||||.|||||.|||||||||||||.....|:|||||.|||
  Fly   451 VVGLTEKVVDGVEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLRPQGSTKIHGKFSFIDL 515

  Fly   426 AGNERGADNSSADRQTRLEGSEINKSLLVLKECIRALGRQSSHLPFRGSKLTQVLRDSFIGGKKV 490
            ||||||.|.||||||||:||:|||||||.|||||||||:||:|||||.|||||||||||| |:|.
  Fly   516 AGNERGVDTSSADRQTRMEGAEINKSLLALKECIRALGKQSAHLPFRVSKLTQVLRDSFI-GEKS 579

  Fly   491 KTCMIAMISPCLHSVEHTLNTLRYADRVKELSVESIPSKRMPDANLGSTSMSDIVCQSSTQRLFP 555
            ||||||||||.|.|.||||||||||||||||.|:.|..                ||
  Fly   580 KTCMIAMISPGLSSCEHTLNTLRYADRVKELVVKDIVE----------------VC--------- 619

  Fly   556 CASSTSMPGGGNQAQQHTN--TANDLNRSQKPTSKPTYPTS----GQQLVQRKGSSQREASMM 612
                   |||..:..:.|:  ...:||... |.|...:|.|    .|...||..:|....:::
  Fly   620 -------PGGDTEPIEITDDEEEEELNMVH-PHSHQLHPNSHAPASQSNNQRAPASHHSGAVI 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59C	NP_611759.1	KISc_KIF2_like	187..519	CDD:276818	234/331 (71%)
		Kinesin	193..520	CDD:278646	230/326 (71%)
Klp10A	NP_001285109.1	KISc_KIF2_like	278..608	CDD:276818	234/331 (71%)
		Kinesin	284..609	CDD:278646	230/326 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438275
Domainoid	1	1.000	319	1.000	Domainoid score	I283
eggNOG	1	0.900	-	-		E2759_KOG0246
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	329	1.000	Inparanoid score	I681
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D202066at33208
OrthoFinder	1	1.000	-	-		FOG0001531
OrthoInspector	1	1.000	-	-		mtm1030
orthoMCL	1	0.900	-	-		OOG6_100492
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3177
SonicParanoid	1	1.000	-	-		X866
	12	11.830