DRSC/TRiP Functional Genomics Resources

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Protein Alignment Klp59C and Klp3A

DIOPT Version :10

Sequence 1:NP_611759.1 Gene:Klp59C / 37671 FlyBaseID:FBgn0034824 Length:626 Species:Drosophila melanogaster
Sequence 2:NP_525053.1 Gene:Klp3A / 31240 FlyBaseID:FBgn0011606 Length:1212 Species:Drosophila melanogaster


Alignment Length:451 Identity:143/451 - (31%)
Similarity:219/451 - (48%) Gaps:83/451 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   179 TNERINCHQIMVCVRKRPLRRKEL-------ADREQDVVSIPSKHTLVVHEPRKHVNLVKFLENH 236
            ::|..:|  :.|.:|.|||.:.||       .:|..|            ..|:..||     .|.
  Fly     2 SSEDPSC--VAVALRVRPLVQSELDRGCRIAVERSAD------------GAPQVTVN-----RNE 47

  Fly   237 SFRFDYVFDEECSNATVYEFTARPLIKHIFDGGMATCFAYGQTGSGKTYTMGGQFPGRHQSSMDG 301
            |:.::||||.:.|...::|...:..:|.:.:|...|..||||||||||||||..|.|.....: |
  Fly    48 SYTYNYVFDIDDSQKDLFETCVQAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNGVLDDHV-G 111

  Fly   302 IYAMAAKDVFSTLKTVPYNKLNLKVYCSFFEIYGTRVFDLLMP---GKPQLRVLEDRNQQVQVVG 363
            :...|..|:|:.:..: .::....|.|||.|:|..:.:||...   .|..:.:.|.:| ::.:.|
  Fly   112 VIPRAVHDIFTAIAEM-QSEFRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIREVKN-RIIMPG 174

  Fly   364 LTQNPVQNTAEVLDLLELGNSVRTSGHTSANSKSSRSHAVFQIVLRSAAGEKLHGK-------FS 421
            ||:..|.:..:|.|.|..|::.|....|:.|..||||||:|.:.|   ...||.||       |:
  Fly   175 LTELVVTSAQQVTDHLIRGSAGRAVAATAMNETSSRSHAIFTLTL---VATKLDGKQSVTTSRFN 236

  Fly   422 LIDLAGNERGADN-SSADRQTRLEGSEINKSLLVLKECIRAL--GRQSSHLPFRGSKLTQVLRDS 483
            |:||||:||.:.. :|.||..  ||..|||.||.|...|.||  |:.:.::|:|.||||::|:||
  Fly   237 LVDLAGSERCSKTLASGDRFK--EGVNINKGLLALGNVINALGSGQAAGYIPYRQSKLTRLLQDS 299

  Fly   484 FIGGKKVKTCMIAMISPCLHSVEHTLNTLRYADR-------------------------VKELSV 523
             :||..: |.|||.:||..::|..||:|||||||                         :::|.|
  Fly   300 -LGGNSI-TLMIACVSPADYNVAETLSTLRYADRALQIKNKPVVNLDPHAAEVNMLKDVIQKLRV 362

  Fly   524 ESIPSKRMPD---ANLGSTSMSDIVCQSSTQRLFPCASSTSMPGGGNQAQQHTNTANDLNR 581
            |.:...:|..   :.:|:..:..|.|:.|      .|.|.:......:.::...|..|.||
  Fly   363 ELLSGGKMSSSLISAVGAAGLGAIPCEES------LAGSMANAAEIQRLKEQVRTLQDRNR 417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Klp59CNP_611759.1 KISc_KIF2_like 187..519 CDD:276818 127/376 (34%)
Klp3ANP_525053.1 KISc_KIF4 7..336 CDD:276823 128/357 (36%)
Smc <453..>985 CDD:440809
Metallothio <1071..1115 CDD:395080
Blue background indicates that the domain is not in the aligned region.

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