Protein Alignment Klp59C and klp-7

DIOPT Version :10

• Sequence 1: NP_611759.1
• Gene: Klp59C / 37671
• FlyBaseID: FBgn0034824
• Length: 626
• Species: Drosophila melanogaster
• Sequence 2: NP_001022677.1
• Gene: klp-7 / 176511
• WormBaseID: WBGene00002219
• Length: 747
• Species: Caenorhabditis elegans
• Alignment Length: 708
• Identity: 276/708 - (38%)
• Similarity: 377/708 - (53%)
• Gaps: 124/708 - (17%)

  Fly     4 LSIEQKIFIRRSDGRVHLAEIIKLEGGDSKLITVEWPEGHTVRGKELPLELVVLMNPHIF----- 63
            |.:...:.|:|||||:|.|.|.:::....  ..|||.|....:|||..||.::.:||.:.
 Worm    60 LVVGMHVEIKRSDGRIHGAVIAEVKSNGR--FMVEWYEKGETKGKESSLEELLTLNPSLQAPKPT 122

  Fly    64 ---DSPRCSGGNAASANQTASISPRSM----------------------KQRIATGSLS---PVL 100
               ..|:.:...:.:.|:...|..:||                      ..:..||:.:   ||
 Worm   123 PPPQPPQKTLQASTAVNRQNGIHAQSMILDDEDTFLLDHINMIPAKGASANKRPTGAFTQHVPV- 186

  Fly   101 ATAPPRQ-----QTAPPVREDEV------------------------VHQAER------------ 124
            ..|||.:     :.||..:||..                        .|.|.|
 Worm   187 RMAPPSEKPLPTRRAPSPKEDAAPAPKSTRTTAAFKPDLDSTAITVPKHTARRTVVVAPAPAPVP 251

  Fly   125 ------MRKERERRREAQART--RLDREQGKNE-DPGNPNWEVARMIRLQREQMESQRVRSGTTN 180
                  |..:|.....|:..:  .:.|...:.: .|.|.|:..|.|||..|.|::   .|..:..
 Worm   252 APPIANMTSQRAPSPVARVPSPKNVPRSYPQQDVQPSNGNFAFAEMIRNYRAQID---YRPLSMF 313

  Fly   181 ERINCHQIMVCVRKRPLRRKELADREQDVVSIPSKHTLVVHEPRKHVNLVKFLENHSFRFDYVFD 245
            :.:|.::|.||||||||.:|||...|.||::|||:...::|:|:..|:|.|:|:|..|||||.||
 Worm   314 DGVNENRISVCVRKRPLNKKELTKAEVDVITIPSRDITILHQPQTRVDLTKYLDNQKFRFDYSFD 378

  Fly   246 EECSNATVYEFTARPLIKHIFDGGMATCFAYGQTGSGKTYTMGGQFPGRHQSSMDGIYAMAAKDV 310
            |..:|..||.|||.||:|.:||.|.||||||||||||||:||||.|.|:.|::..||||:.|:||
 Worm   379 EYANNELVYRFTAAPLVKTVFDNGTATCFAYGQTGSGKTHTMGGDFSGKKQNASMGIYALTARDV 443

  Fly   311 FSTLKTVPYNKLNLKVYCSFFEIYGTRVFDLLMPGKPQLRVLEDRNQQVQVVGLTQNPVQNTAEV 375
            |..|:...|.:.:|.|:|:|||||||:.:||| ..|.:||||||:.|:||||||.:....|..:|
 Worm   444 FRMLEQPQYRRKDLSVHCAFFEIYGTKTYDLL-NDKAELRVLEDKMQKVQVVGLKEEQAHNEQDV 507

  Fly   376 LDLLELGNSVRTSGHTSANSKSSRSHAVFQIVLRSAAGEKLHGKFSLIDLAGNERGADNSSADRQ 440
            |:|:..|..|||:|.||||:.||||||:|||:||.  |:|:.||||||||||||||.|....||.
 Worm   508 LELINKGTLVRTAGTTSANANSSRSHAIFQIILRQ--GKKVWGKFSLIDLAGNERGQDTRECDRD 570

  Fly   441 TRLEGSEINKSLLVLKECIRALGRQSSHLPFRGSKLTQVLRDSFIGGKKVKTCMIAMISPCLHSV 505
            ||.||:.||.|||.||||||.:.|.|||:|||.||||.||||||| |:|.:|.||:||||.:.|.
 Worm   571 TRKEGANINTSLLALKECIRGMARNSSHVPFRQSKLTMVLRDSFI-GEKSRTVMISMISPGISSS 634

  Fly   506 EHTLNTLRYADRVKEL----SVESIPSK-----RMPDANLGSTSMSDIVCQSSTQRLFPCASSTS 561
            :||||||||||||||:    |.|:.|.:     ..|.|:.......::|
 Worm   635 DHTLNTLRYADRVKEMGTDGSGEATPIRDEELFLPPSADKSDEEYDEMV---------------- 683

  Fly   562 MPGGGNQAQQHTNTANDLNRSQKPTSKPTYPTSGQQLVQRKGSSQREASMMLTKSLAQ 619
                  :.|:|...|.|..|:.|..|:.....:...|.....::|:...:.....|||
 Worm   684 ------EKQEHRRVAVDHVRNLKDMSEKIIRETTIVLSNEPSAAQKAECLAKLDQLAQ 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp59C	NP_611759.1	KISc_KIF2_like	187..519	CDD:276818	200/331 (60%)
klp-7	NP_001022677.1	PHA03378	<161..299	CDD:223065	23/138 (17%)
		KISc_KIF2_like	320..648	CDD:276818	200/331 (60%)