DRSC/TRiP Functional Genomics Resources

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Protein Alignment RpL37-2 and Kcnq1

DIOPT Version :10

Sequence 1:NP_611757.1 Gene:RpL37-2 / 37669 FlyBaseID:FBgn0034822 Length:89 Species:Drosophila melanogaster
Sequence 2:NP_114462.2 Gene:Kcnq1 / 84020 RGDID:621503 Length:669 Species:Rattus norvegicus


Alignment Length:33 Identity:12/33 - (36%)
Similarity:13/33 - (39%) Gaps:13/33 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly    56 RKAQGTGRMRYLKNLRRRFRNGLREG--GAAKK 86
            ||..|.||:.           |.|.|  |.|||
  Rat    12 RKRAGWGRLL-----------GARRGSAGLAKK 33

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RpL37-2NP_611757.1 PTZ00073 1..89 CDD:240257 12/33 (36%)
Kcnq1NP_114462.2 Ion_trans 123..359 CDD:459842
Interaction with KCNE3. /evidence=ECO:0000250|UniProtKB:P51787 238..246
Interaction with CALM. /evidence=ECO:0000250|UniProtKB:P51787 370..382
KCNQ_channel <511..617 CDD:460954
Interaction with CALM, calcium-dependent. /evidence=ECO:0000250|UniProtKB:P51787 515..529
Interaction with KCNE1 C-terminus. /evidence=ECO:0000250|UniProtKB:P51787 535..572
Interaction with AKAP9. /evidence=ECO:0000250|UniProtKB:P51787 588..616
C-terminal assembly domain (tetramerization). /evidence=ECO:0000250|UniProtKB:P51787 589..620
Blue background indicates that the domain is not in the aligned region.

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