DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL37b and kcnd2

DIOPT Version :9

Sequence 1:	NP_611757.1	Gene:	RpL37b / 37669	FlyBaseID:	FBgn0034822	Length:	89	Species:	Drosophila melanogaster
Sequence 2:	NP_001076336.1	Gene:	kcnd2 / 570188	ZFINID:	ZDB-GENE-041210-70	Length:	630	Species:	Danio rerio

Alignment Length:	114	Identity:	28/114 - (24%)
Similarity:	39/114 - (34%)	Gaps:	42/114 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTKGTTSFGKRHNKT------HTICRRCG-------------NSS--YHLQKSKCSQCGYPAAKT 44
            :|..|..:|....||      .:||...|             |.|  ||..:.        |.|.
Zfish   365 VTMTTLGYGDMVPKTIMGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQSQR--------AEKR 421

  Fly    45 RSFNWSRKAKGRKAQGTGRMRYLKNLRRRFRNGL---------REGGAA 84
            |:...:|.|:.|.|:..|...||:..    |||:         :|.|.|
Zfish   422 RAQKKTRLARIRAAKSGGANAYLQYK----RNGMLVDMEEEASKEAGQA 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL37b	NP_611757.1	PTZ00073	1..89	CDD:240257	28/114 (25%)
kcnd2	NP_001076336.1	Shal-type	3..28	CDD:288455
		BTB	42..139	CDD:197585
		BTB_2	42..131	CDD:280393
		Ion_trans	228..416	CDD:278921	12/50 (24%)
		Ion_trans_2	330..410	CDD:285168	9/44 (20%)
		DUF3399	444..548	CDD:288712	7/27 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900