DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment RpL37-2 and KCND3

DIOPT Version :10

Sequence 1:NP_611757.1 Gene:RpL37-2 / 37669 FlyBaseID:FBgn0034822 Length:89 Species:Drosophila melanogaster
Sequence 2:NP_004971.2 Gene:KCND3 / 3752 HGNCID:6239 Length:655 Species:Homo sapiens


Alignment Length:32 Identity:11/32 - (34%)
Similarity:13/32 - (40%) Gaps:5/32 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 THTICRRCGNSSYHLQKSKCSQCGYPAAKTRS 46
            |.|.|.|....:.||..|     ..||.:.||
Human   543 TTTCCSRRSKKTTHLPNS-----NLPATRLRS 569

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RpL37-2NP_611757.1 PTZ00073 1..89 CDD:240257 11/32 (34%)
KCND3NP_004971.2 BTB_POZ_KCND3 6..143 CDD:349726
Interaction with KCNIP1 and KCNIP2. /evidence=ECO:0000269|PubMed:17187064, ECO:0000269|PubMed:34997220 6..21
Interaction with KCNIP1. /evidence=ECO:0000269|PubMed:17187064 70..78
Ion_trans 186..412 CDD:459842
Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 367..372
DUF3399 468..563 CDD:463381 7/24 (29%)
Interaction with KCNIP1 and KCNIP2. /evidence=ECO:0000269|PubMed:34997220 470..487
Mediates dendritic targeting. /evidence=ECO:0000250|UniProtKB:Q63881 472..487
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 525..565 8/26 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 615..655
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.