DRSC/TRiP Functional Genomics Resources

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Protein Alignment RpL37-2 and KCNB1

DIOPT Version :10

Sequence 1:NP_611757.1 Gene:RpL37-2 / 37669 FlyBaseID:FBgn0034822 Length:89 Species:Drosophila melanogaster
Sequence 2:NP_004966.1 Gene:KCNB1 / 3745 HGNCID:6231 Length:858 Species:Homo sapiens


Alignment Length:67 Identity:17/67 - (25%)
Similarity:27/67 - (40%) Gaps:13/67 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 TSFGK-RHNKTH-TICRRCGNSSYHLQKSKCSQCGYPAAKTRSFNWSRKAKGRKAQGTGRMRYLK 68
            |..|| |...|| ::...|  ..|.|..::.....:|.|.|...|:.|         |||:..::
Human    55 TRLGKLRDCNTHDSLLEVC--DDYSLDDNEYFFDRHPGAFTSILNFYR---------TGRLHMME 108

  Fly    69 NL 70
            .:
Human   109 EM 110

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RpL37-2NP_611757.1 PTZ00073 1..89 CDD:240257 17/67 (25%)
KCNB1NP_004966.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
BTB_POZ_KCNB2 15..141 CDD:349719 17/67 (25%)
Self-association. /evidence=ECO:0000250|UniProtKB:P15387 59..75 5/17 (29%)
Ion_trans 188..424 CDD:459842
Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 377..382
Self-association. /evidence=ECO:0000250|UniProtKB:P15387 448..481
Kv2channel 467..679 CDD:397541
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 471..524
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 538..574
FFAT. /evidence=ECO:0000269|PubMed:33124732 590..596
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 770..807
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 836..858
Blue background indicates that the domain is not in the aligned region.

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