DRSC/TRiP Functional Genomics Resources

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Protein Alignment RpL37-2 and KCNA6

DIOPT Version :10

Sequence 1:NP_611757.1 Gene:RpL37-2 / 37669 FlyBaseID:FBgn0034822 Length:89 Species:Drosophila melanogaster
Sequence 2:NP_002226.1 Gene:KCNA6 / 3742 HGNCID:6225 Length:529 Species:Homo sapiens


Alignment Length:103 Identity:22/103 - (21%)
Similarity:32/103 - (31%) Gaps:29/103 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MTKGTTSFGKRHNKT------HTICRRCG---------------NSSYHLQKSKCSQ-------C 37
            :|..|..:|..:..|      .::|...|               |..||.:..:..|       |
Human   418 VTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHVTC 482

  Fly    38 GYPAAKTRSF-NWSRKAKGRKAQGTGRMRYLKNLRRRF 74
            |.||...|:. |...|....:|....|..||....|.:
Human   483 GQPAPDLRATDNGLGKPDFPEANRERRPSYLPTPHRAY 520

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RpL37-2NP_611757.1 PTZ00073 1..89 CDD:240257 22/103 (21%)
KCNA6NP_002226.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..33
BTB_POZ_KCNA6 41..170 CDD:349714
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 210..233
Ion_trans 259..468 CDD:459842 9/49 (18%)
S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142 360..373
Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 422..427 1/4 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 488..513 5/24 (21%)
PDZ-binding. /evidence=ECO:0000255 527..529
Blue background indicates that the domain is not in the aligned region.

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