DRSC/TRiP Functional Genomics Resources

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Protein Alignment RpL37-2 and KCNA5

DIOPT Version :10

Sequence 1:NP_611757.1 Gene:RpL37-2 / 37669 FlyBaseID:FBgn0034822 Length:89 Species:Drosophila melanogaster
Sequence 2:NP_002225.2 Gene:KCNA5 / 3741 HGNCID:6224 Length:613 Species:Homo sapiens


Alignment Length:39 Identity:11/39 - (28%)
Similarity:17/39 - (43%) Gaps:12/39 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    63 RMRYLKNLRRRF---RN-----GL----REGGAAKKKTN 89
            |:||...||..:   ||     |:    :.||..::..|
Human   152 RLRYFDPLRNEYFFDRNRPSFDGILYYYQSGGRLRRPVN 190

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RpL37-2NP_611757.1 PTZ00073 1..89 CDD:240257 10/37 (27%)
KCNA5NP_002225.2 Tetramerization domain. /evidence=ECO:0000305|PubMed:20018952 1..211 11/39 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..108
2 X 11 AA tandem repeat of D-[SP]-G-V-R-P-L-P-P-L-P 61..82
BTB_POZ 120..246 CDD:453885 11/39 (28%)
Ion_trans 249..526 CDD:459842
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 282..304
S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142 418..431
Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 480..485
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 532..559
PDZ-binding. /evidence=ECO:0000250 611..613
Blue background indicates that the domain is not in the aligned region.

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