Protein Alignment CG9876 and ALX4

DIOPT Version :10

• Sequence 1: NP_611756.1
• Gene: CG9876 / 37668
• FlyBaseID: FBgn0034821
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_068745.2
• Gene: ALX4 / 60529
• HGNCID: 450
• Length: 411
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 80/232 - (34%)
• Similarity: 101/232 - (43%)
• Gaps: 63/232 - (27%)

  Fly    83 SSNFGPTGAGCGG------ADRPAPCSGNLPAGGGHHSRKPRRNRTTFSSAQLTALEKVFERTHY 141
            ||......||..|      :|.|:|..   .|....:..|.|||||||:|.||..|||||::|||
Human   177 SSYLSVKEAGVKGPQDRASSDLPSPLE---KADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHY 238

  Fly   142 PDAFVREELATKVHLSEARVQVWFQNRRAKFRRNERSVGS----RTLLDTAPQLVPAPISNNMHK 202
            ||.:.||:||.:..|:||||||||||||||:|:.|| .|.    ||...||.:|   |:......
Human   239 PDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRER-FGQMQQVRTHFSTAYEL---PLLTRAEN 299

  Fly   203 YANM------------------------------PHPHPQPPPPPGAYALNFGPLELRSCQNYTN 237
            ||.:                              ||.|     |||:.|        .|..::.:
Human   300 YAQIQNPSWLGNNGAASPVPACVVPCDPVPACMSPHAH-----PPGSGA--------SSVTDFLS 351

  Fly   238 CYGGFGSSGASGSGVCSFFGATNYCVAAN-YAKNAYP 273
            ..|.....|.:..|  |.|||.:.....| |..|..|
Human   352 VSGAGSHVGQTHMG--SLFGAASLSPGLNGYELNGEP 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9876	NP_611756.1	Homeodomain	118..174	CDD:459649	39/55 (71%)
ALX4	NP_068745.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..145
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	184..219		11/37 (30%)
		Homeodomain	215..271	CDD:459649	39/55 (71%)
		OAR	387..405	CDD:461067	80/232 (34%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	391..404