Protein Alignment CG9876 and Pitx2

DIOPT Version :10

• Sequence 1: NP_611756.1
• Gene: CG9876 / 37668
• FlyBaseID: FBgn0034821
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_001035970.1
• Gene: Pitx2 / 54284
• RGDID: 3331
• Length: 324
• Species: Rattus norvegicus
• Alignment Length: 221
• Identity: 63/221 - (28%)
• Similarity: 87/221 - (39%)
• Gaps: 69/221 - (31%)

  Fly    52 RNLD-KIHRFSVDNIMEMKH-DAYSKGKMAMELSSNFGPTGAGCG-GADRPAPCSGNLPAGGGHH 113
            |:|| ..||..|..|.:... :...|.|         |..|.... ||:.|:            .
  Rat    45 RSLDASKHRLEVHTISDTSSPEVAEKDK---------GQQGKNEDVGAEDPS------------K 88

  Fly   114 SRKPRRNRTTFSSAQLTALEKVFERTHYPDAFVREELATKVHLSEARVQVWFQNRRAKFRRNERS 178
            .::.||.||.|:|.||..||..|:|..|||...|||:|...:|:||||:|||:|||||:|:.||:
  Rat    89 KKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERN 153

  Fly   179 VGSRTLLDTAPQLVPAPISNNMHKYANMPHPHPQPPPPPGAYALNFGPLELRSCQNYTNCYGGFG 243
                         ..|.:..|                       .|||......|.|.:.|.|:.
  Rat   154 -------------QQAELCKN-----------------------GFGPQFNGLMQPYDDMYPGYS 182

  Fly   244 SSGASGSGVCS---------FFGATN 260
            .:..:..|:.|         ||.:.|
  Rat   183 YNNWAAKGLTSASLSTKSFPFFNSMN 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9876	NP_611756.1	Homeodomain	118..174	CDD:459649	32/55 (58%)
Pitx2	NP_001035970.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	57..111		18/74 (24%)
		Homeodomain	93..149	CDD:459649	32/55 (58%)
		OAR	282..299	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	286..299
		Nuclear localization signal. /evidence=ECO:0000255	292..296