Protein Alignment CG9876 and PRRX1

DIOPT Version :10

• Sequence 1: NP_611756.1
• Gene: CG9876 / 37668
• FlyBaseID: FBgn0034821
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_073207.1
• Gene: PRRX1 / 5396
• HGNCID: 9142
• Length: 245
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 86/200 - (43%)
• Similarity: 114/200 - (56%)
• Gaps: 31/200 - (15%)

  Fly    31 SSHQSHNLESEDKLEDREESGRNLDKIH---RFSVDNIMEMKHDAYSKGKM-AMELSSNFGPTGA 91
            :|...|.||.:..|..|.:|..|||.:.   .|||.::::::    ..|.| |.:...|.|..|.
Human     2 TSSYGHVLERQPALGGRLDSPGNLDTLQAKKNFSVSHLLDLE----EAGDMVAAQADENVGEAGR 62

  Fly    92 G-------CGGADRPAPCSGNLPAGGGHHSRKPRRNRTTFSSAQLTALEKVFERTHYPDAFVREE 149
            .       ..|:|.|...:..|.: .....||.|||||||:|:||.|||:||||||||||||||:
Human    63 SLLESPGLTSGSDTPQQDNDQLNS-EEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVRED 126

  Fly   150 LATKVHLSEARVQVWFQNRRAKFRRNERSV---GSRTLLDTAPQLVPA---PISNNMHKYANMPH 208
            ||.:|:|:||||||||||||||||||||::   .:.:||.:....|.|   ||         :|.
Human   127 LARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPI---------VPR 182

  Fly   209 PHPQP 213
            |.|:|
Human   183 PAPRP 187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9876	NP_611756.1	Homeodomain	118..174	CDD:459649	46/55 (84%)
PRRX1	NP_073207.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		6/19 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..103		13/40 (33%)
		Homeodomain	99..151	CDD:459649	42/51 (82%)
		OAR	219..235	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	222..235