Protein Alignment CG9876 and OTX2

DIOPT Version :10

• Sequence 1: NP_611756.1
• Gene: CG9876 / 37668
• FlyBaseID: FBgn0034821
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_068374.1
• Gene: OTX2 / 5015
• HGNCID: 8522
• Length: 297
• Species: Homo sapiens
• Alignment Length: 190
• Identity: 66/190 - (34%)
• Similarity: 85/190 - (44%)
• Gaps: 52/190 - (27%)

  Fly   100 APCSGNLPAGGGHHSRKPRRNRTTFSSAQLTALEKVFERTHYPDAFVREELATKVHLSEARVQVW 164
            |.|....|       ||.||.||||:.|||..||.:|.:|.|||.|:|||:|.|::|.|:|||||
Human    36 ASCPAATP-------RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVW 93

  Fly   165 FQNRRAKFRRNE---------------------RSVGSRTLLDTAPQLVPAPISNNMHKYANMPH 208
            |:|||||.|:.:                     |.|.|.:  .|:.|..| |.|.::...|:...
Human    94 FKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSES--GTSGQFTP-PSSTSVPTIASSSA 155

  Fly   209 PHPQPPPPPGAYALNFGPLE-----LRSC------QNYTNCYGGFGSSGASGSGVCSFFG 257
            |.....|      .:..||.     ..||      ..||...|  .|.|.:||  .|:||
Human   156 PVSIWSP------ASISPLSDPLSTSSSCMQRSYPMTYTQASG--YSQGYAGS--TSYFG 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9876	NP_611756.1	Homeodomain	118..174	CDD:459649	35/55 (64%)
OTX2	NP_068374.1	Homeodomain	47..102	CDD:459649	35/54 (65%)
		TF_Otx	161..242	CDD:427350	15/55 (27%)