Protein Alignment CG9876 and PHOX2A

DIOPT Version :10

• Sequence 1: NP_611756.1
• Gene: CG9876 / 37668
• FlyBaseID: FBgn0034821
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_001412025.1
• Gene: PHOX2A / 401
• HGNCID: 691
• Length: 312
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 86/296 - (29%)
• Similarity: 106/296 - (35%)
• Gaps: 129/296 - (43%)

  Fly    71 DAYSKGKMAMELSSNFGPTGAGC---GGAD----RPA------PC----SGNLPAG--------- 109
            ::|.....|||.|: :|..|| |   ||..    |||      ||    |.|...|
Human     7 NSYDSCVAAMEASA-YGDFGA-CSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALGALRDHQPAP 69

  Fly   110 -------------GGHHSRKPRRNRTTFSSAQLTALEKVFERTHYPDAFVREELATKVHLSEARV 161
                         |.|..||.||.||||:||||..||:||..|||||.:.|||||.|:.|:||||
Human    70 YSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARV 134

  Fly   162 ----------------------------QVWFQNRRAKFRRNERSVGSRTLLDTA---------- 188
                                        ||||||||||||:.||:..::.....|
Human   135 QDLTRALRPRADPVRSPTLVQADWPLCPQVWFQNRRAKFRKQERAASAKGAAGAAGAKKGEARCS 199

  Fly   189 -------------------------------PQLVPAPISNNMHKYANMPHPHPQPPPPPGAYAL 222
                                           |:|.|:|:...:   .:.|.|.|.|.|..||.
Human   200 SEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLSPSPLPVAL---GSGPGPGPGPQPLKGAL-- 259

  Fly   223 NFGPLELRSCQNYTNCYGGFGSSGASGSGVCSFFGA 258
                        :....||.|  |..|:|......|
Human   260 ------------WAGVAGGGG--GGPGAGAAELLKA 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9876	NP_611756.1	Homeodomain	118..174	CDD:459649	41/83 (49%)
PHOX2A	NP_001412025.1	Homeodomain	91..175	CDD:459649	41/83 (49%)