Protein Alignment CG9876 and HOXD3

DIOPT Version :10

• Sequence 1: NP_611756.1
• Gene: CG9876 / 37668
• FlyBaseID: FBgn0034821
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_008829.3
• Gene: HOXD3 / 3232
• HGNCID: 5137
• Length: 432
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 68/298 - (22%)
• Similarity: 102/298 - (34%)
• Gaps: 108/298 - (36%)

  Fly    12 PVGNPGNFYYGPTVSGEIYSSHQSHNLESEDKLEDREESGRNLDKIHRFSVDNIMEMKHDAYSKG 76
            |.|.|.......|:|.:|:..              .:||.:|                    ||.
Human   143 PKGGPNASSSSATISKQIFPW--------------MKESRQN--------------------SKQ 173

  Fly    77 KMAMELSSNFGPTGAGCGGADRPAPCSGNLPAGGGHHSRKPRRNRTTFSSAQLTALEKVFERTHY 141
            |      ::....|..|.....|.|.|              :|.||.::||||..|||.|....|
Human   174 K------NSCATAGESCEDKSPPGPAS--------------KRVRTAYTSAQLVELEKEFHFNRY 218

  Fly   142 PDAFVREELATKVHLSEARVQVWFQNRRAKFRRNERSVG------SRTLLDTAP----------- 189
            .....|.|:|..::|:|.::::||||||.|:::::::.|      |::...:.|
Human   219 LCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYS 283

  Fly   190 -QLVPAPISNNMHKYANMPHPHPQPP----PPPGAYALNFGPLELRSCQNYTNCY---------- 239
             ||.|.|         .:.:..|.||    ..|..|.|......|.||......|
Human   284 GQLPPVP---------GLAYDAPSPPAFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPM 339

  Fly   240 ----GGFGSSGASGSGVCSFFGATNYCVAANYAKNAYP 273
                |||.|:...||.|         .|..|:.::..|
Human   340 ASNGGGFASANLQGSPV---------YVGGNFVESMAP 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9876	NP_611756.1	Homeodomain	118..174	CDD:459649	24/55 (44%)
HOXD3	NP_008829.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..62
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..197		17/107 (16%)
		Antp-type hexapeptide	160..165		1/18 (6%)
		Homeodomain	195..251	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	253..280		3/26 (12%)
		DUF4074	369..430	CDD:463833	68/298 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	400..432