DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9876 and isl2b

DIOPT Version :9

Sequence 1:	NP_611756.1	Gene:	CG9876 / 37668	FlyBaseID:	FBgn0034821	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_571039.1	Gene:	isl2b / 30151	ZFINID:	ZDB-GENE-990415-133	Length:	358	Species:	Danio rerio

Alignment Length:	203	Identity:	60/203 - (29%)
Similarity:	84/203 - (41%)	Gaps:	53/203 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 GCGGADRPAPCS-GNLPAGGGH-------------------HSRKPRRNRTTFSSAQLTALEKVF 136
            |.||    :|.| ||:...|.|                   .|.|..|.||..:..||..|...:
Zfish   150 GPGG----SPLSPGNIHTRGLHMAADPVSVRQTPHRNHVHKQSEKTTRVRTVLNEKQLHTLRTCY 210

  Fly   137 ERTHYPDAFVREELATKVHLSEARVQVWFQNRRAKFRRNERSV---------GSRTLLD--TAPQ 190
            .....|||.::|:|.....||...::|||||:|.|.::  ||:         |.:|.|.  |...
Zfish   211 NANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK--RSILMKQLQQQHGDKTNLQGMTGTA 273

  Fly   191 LVP-APISNNMHKYANMPHPHP------QPP-PPPGAYALNFGPLELRSCQNYTNCYGGFGSSG- 246
            ||. :||.:|    .::| .||      ||| .....:||. ..|:..:.|...: :...||.|
Zfish   274 LVAGSPIRHN----PSVP-GHPVDVQAYQPPWKALSEFALQ-SDLDQPAFQQLVS-FSESGSLGN 331

  Fly   247 ASGSGVCS 254
            :|||.|.|
Zfish   332 SSGSDVTS 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9876	NP_611756.1	Homeobox	121..173	CDD:278475	19/51 (37%)
isl2b	NP_571039.1	LIM1_Isl	27..81	CDD:188752
		LIM2_Isl2	89..143	CDD:188855
		HOX	191..247	CDD:197696	20/55 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	325..358		8/15 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000