DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG9876 and Otx1

DIOPT Version :10

Sequence 1:NP_611756.1 Gene:CG9876 / 37668 FlyBaseID:FBgn0034821 Length:275 Species:Drosophila melanogaster
Sequence 2:NP_037241.2 Gene:Otx1 / 25646 RGDID:3237 Length:355 Species:Rattus norvegicus


Alignment Length:243 Identity:64/243 - (26%)
Similarity:98/243 - (40%) Gaps:73/243 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    86 FGPTGAGCGGADRPAPCSGNLPAGGGHHS--RKPRRNRTTFSSAQLTALEKVFERTHYPDAFVRE 148
            :|..|.|..|     |....|....|:.:  ||.||.||||:.:||..||.:|.:|.|||.|:||
  Rat    10 YGMNGLGLAG-----PAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMRE 69

  Fly   149 ELATKVHLSEARVQVWFQNRRAKFRRNERS---------------VGSRTLLDTAPQLVPAPISN 198
            |:|.|::|.|:||||||:|||||.|:.::|               |...:..:::.|..|..:|:
  Rat    70 EVALKINLPESRVQVWFKNRRAKCRQQQQSGNGTKSRPVKKKSSPVRESSGSESSGQFTPPAVSS 134

  Fly   199 NMHKYANMPHPHPQPP----------PPPGAYALN-------FGPLEL----------------- 229
            :....::.......|.          |...|.:|:       :.|..:                 
  Rat   135 SASSSSSASSASANPAAAAAAGLGGNPVAAASSLSTPTASSIWSPASISPGSAPASVSVPEPLGA 199

  Fly   230 ---RSCQNYTNCYG----------GFGSSGASGSGV----CSFFGATN 260
               .||...:...|          .:|..|:.|.|.    .|:||..:
  Rat   200 PSNASCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPAPSSSYFGGVD 247

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9876NP_611756.1 Homeodomain 118..174 CDD:459649 34/55 (62%)
Otx1NP_037241.2 Homeodomain 39..95 CDD:459649 34/55 (62%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 92..144 7/51 (14%)
TF_Otx 178..274 CDD:427350 11/70 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 257..306
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.