DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9876 and Alx1

DIOPT Version :9

Sequence 1:	NP_611756.1	Gene:	CG9876 / 37668	FlyBaseID:	FBgn0034821	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_037053.1	Gene:	Alx1 / 25401	RGDID:	2273	Length:	326	Species:	Rattus norvegicus

Alignment Length:	258	Identity:	76/258 - (29%)
Similarity:	108/258 - (41%)	Gaps:	76/258 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PVGNPGNFYYGPTVSGEIYSSHQSHNLESEDKLEDREESGRNLDKI-------HRFSVDNIMEMK 69
            |.....:||.|  ..|.:  .|....|::| ....:..:|:.:...       |...:|.....:
  Rat    13 PPSKNSDFYMG--TGGAL--EHVMETLDNE-SFYGKATAGKCVQAFGPLPRAEHHVRLDRTSPCQ 72

  Fly    70 HDAYSKGKMAME---LSSNFGPTGAGCGGADRPAP----------------CSGNLPAGGGHHSR 115
            ..:.:.|...:|   |.:.......||... |.:|                |..|:      .|.
  Rat    73 DSSVNYGITKVEGQPLHTELNRAMDGCNNL-RMSPVKGMPEKSELDELGDKCDSNV------SSS 130

  Fly   116 KPRRNRTTFSSAQLTALEKVFERTHYPDAFVREELATKVHLSEARVQVWFQNRRAKFRRNER--- 177
            |.||:||||:|.||..|||||::|||||.:|||:||.:..|:||||||||||||||:|:.||
  Rat   131 KKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQ 195

  Fly   178 --------------SVGSRTLLDTAPQ-------------------LVPAPISNNMHKYANMP 207
                          ||..||  |:.||                   ::|...|:.|..|::.|
  Rat   196 IQQAKSHFAATYDISVLPRT--DSYPQIQNNLWAGNTSGGSVVTSCMLPRDASSCMTPYSHSP 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9876	NP_611756.1	Homeobox	121..173	CDD:278475	37/51 (73%)
Alx1	NP_037053.1	Homeobox	135..188	CDD:278475	37/52 (71%)
		Transactivation domain. /evidence=ECO:0000269\|PubMed:12390248	192..326		13/67 (19%)
		OAR	302..319	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	306..319
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24329
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010