DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9876 and Prrx2

DIOPT Version :9

Sequence 1:	NP_611756.1	Gene:	CG9876 / 37668	FlyBaseID:	FBgn0034821	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	XP_006497869.1	Gene:	Prrx2 / 20204	MGIID:	98218	Length:	259	Species:	Mus musculus

Alignment Length:	195	Identity:	84/195 - (43%)
Similarity:	109/195 - (55%)	Gaps:	40/195 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 FSVDNIMEMKHDAYSKGKMAMELSSNFGPTGAGCGGADRP---------APCSGNLPA--GGGHH 113
            |||.::::::..|.:..:.|..:|   ||..|..|.|..|         ||..|:.|:  .|...
Mouse    33 FSVSHLLDLEEVAAAGRRAAGPVS---GPAEAREGAAREPSGGSSGSEAAPQDGDCPSPGRGTKR 94

  Fly   114 SRKPRRNRTTFSSAQLTALEKVFERTHYPDAFVREELATKVHLSEARV------------QVWFQ 166
            .:|.|||||||:|:||.|||:|||||||||||||||||.:|:||||||            |||||
Mouse    95 KKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQSTRPCSPHSPSQVWFQ 159

  Fly   167 NRRAKFRRNERSV---GSRTLLDTAPQ-------LVPAPISNNMHKYANMPHPHPQ---PPPPPG 218
            |||||||||||::   .|.:||.:..|       :.|.|.:.: ..|.:.|...|.   ||..||
Mouse   160 NRRAKFRRNERAMLATRSASLLKSYGQEAAIEQPVAPRPTTMS-PDYLSWPASSPYSSVPPYSPG 223

Fly 219 218
Mouse 224 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9876	NP_611756.1	Homeobox	121..173	CDD:278475	44/63 (70%)
Prrx2	XP_006497869.1	Homeobox	103..167	CDD:365835	44/63 (70%)
Prrx2	XP_006497869.1	OAR	232..249	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	105	1.000	Domainoid score	I6649
eggNOG	1	0.900	-	-		E33208_3BKNX
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	1	1.000	-	-		otm43542
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3194
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.770