DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9876 and Pax3

DIOPT Version :10

Sequence 1:NP_611756.1 Gene:CG9876 / 37668 FlyBaseID:FBgn0034821 Length:275 Species:Drosophila melanogaster
Sequence 2:NP_001152992.1 Gene:Pax3 / 18505 MGIID:97487 Length:484 Species:Mus musculus


Alignment Length:181 Identity:39/181 - (21%)
Similarity:68/181 - (37%) Gaps:65/181 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 NGNEVSLDRYQG-SVCL---IVNFSTKDATFEKVLSLLTPLLRKYHN-------DTRKDLNVLFF 73
            ||.:|....::| .|.|   :.|||:.:|     ||||     .|.:       |....|:|:|:
Mouse    51 NGKKVMAASWRGLPVVLKSKLENFSSYEA-----LSLL-----DYPDGGAGGGEDELSPLDVVFY 105

  Fly    74 PCFQFGSK---ESPDEIV------QRFESSTD--SSGMIGEIFTEIEVNGSKAPGLYKYLK---- 123
            ...:..:.   |:.:.:.      ||.:.|..  |...:..::..::...      |.:|:    
Mouse   106 ATLEIKNSLGLETGNNLTLPRLWGQRLKESERMYSRAELASLWALLQQEE------YTFLRVLQD 164

  Fly   124 -----AKKPGNCGGFINSNFTIFLTDRQGVPVERLNAG----IHPYTLEDM 165
                 ||..|:||.|              ..||.|.||    .|.::|:::
Mouse   165 LTNHVAKILGSCGHF--------------YAVEYLAAGHAWDQHIFSLDEL 201

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9876NP_611756.1 Homeodomain 118..174 CDD:459649 15/61 (25%)
Pax3NP_001152992.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
PAX 34..159 CDD:128645 25/123 (20%)
PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381 37..93 15/51 (29%)
RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381 113..161 7/53 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 165..228 13/51 (25%)
Homeodomain 220..276 CDD:459649
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 309..351
Pax7 347..391 CDD:403540
Blue background indicates that the domain is not in the aligned region.

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