Protein Alignment CG9876 and DLX2

DIOPT Version :10

• Sequence 1: NP_611756.1
• Gene: CG9876 / 37668
• FlyBaseID: FBgn0034821
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_004396.1
• Gene: DLX2 / 1746
• HGNCID: 2915
• Length: 328
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 72/265 - (27%)
• Similarity: 105/265 - (39%)
• Gaps: 58/265 - (21%)

  Fly     4 YQQQLHSLPVGNPGNFYYGPTVSGEIYSSHQSHNLESEDKLEDREESGRNLDKIHRFSVDNIMEM 68
            |..|.|  |.|..|.       .|..|:...|:..::         ||.|          |:...
Human    67 YTNQQH--PAGGGGG-------GGSPYAHMGSYQYQA---------SGLN----------NVPYS 103

  Fly    69 KHDAYSKGKMAMELSSNFGPTGAGCGGADRPAPCSGNLP----AGGGHHSRKPRRNRTTFSSAQL 129
            ...:|..|..|...|  :.|.|.....|:.........|    ..|  ..:|.|:.||.:||.||
Human   104 AKSSYDLGYTAAYTS--YAPYGTSSSPANNEPEKEDLEPEIRIVNG--KPKKVRKPRTIYSSFQL 164

  Fly   130 TALEKVFERTHYPDAFVREELATKVHLSEARVQVWFQNRRAKFRRNERSVGSRTLLDTAPQLVPA 194
            .||::.|::|.|.....|.|||..:.|::.:|::||||||:||::..:|               .
Human   165 AALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWKS---------------G 214

  Fly   195 PISNNMHKYANMPHPHPQPP-PPPGAYALNFG-PLELRSCQNYTNCYGGFGSSGASGSGVCS-FF 256
            .|.:..|..|:...|...|| ..|.::  :|| |..:.......:...|.||||:|.|...| |.
Human   215 EIPSEQHPGASASPPCASPPVSAPASW--DFGVPQRMAGGGGPGSGGSGAGSSGSSPSSAASAFL 277

  Fly   257 GATNY 261
            |  ||
Human   278 G--NY 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9876	NP_611756.1	Homeodomain	118..174	CDD:459649	26/55 (47%)
DLX2	NP_004396.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..81		6/22 (27%)
		DLL_N	51..132	CDD:463567	20/94 (21%)
		Homeodomain	153..209	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	211..270		17/75 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..328