DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9876 and Alx4

DIOPT Version :9

Sequence 1:	NP_611756.1	Gene:	CG9876 / 37668	FlyBaseID:	FBgn0034821	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_031468.1	Gene:	Alx4 / 11695	MGIID:	108359	Length:	399	Species:	Mus musculus

Alignment Length:	225	Identity:	79/225 - (35%)
Similarity:	99/225 - (44%)	Gaps:	63/225 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 TGAGCGGADRPAPCSGNLPA-----GGGHHSRKPRRNRTTFSSAQLTALEKVFERTHYPDAFVRE 148
            |||. |..||   .|..:|:     ....:..|.|||||||:|.||..|||||::|||||.:.||
Mouse   173 TGAK-GPQDR---ASAEIPSPLEKTDSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYARE 233

  Fly   149 ELATKVHLSEARVQVWFQNRRAKFRRNERSVGS----RTLLDTAPQLVPAPISNNMHKYANM--- 206
            :||.:..|:||||||||||||||:|:.|| .|.    ||...||.:|   |:......||.:
Mouse   234 QLAMRTDLTEARVQVWFQNRRAKWRKRER-FGQMQQVRTHFSTAYEL---PLLTRAENYAQIQNP 294

  Fly   207 ---------------------------PHPHPQPPPPPGAYALNFGPLELRSCQNYTNCYGGFGS 244
                                       ||.|     |||:.|        .|..::.:..|....
Mouse   295 SWIGNNGAASPVPACVVPCDPVPACMSPHAH-----PPGSGA--------SSVSDFLSVSGAGSH 346

  Fly   245 SGASGSGVCSFFGATNYCVAAN-YAKNAYP 273
            .|.:..|  |.|||.......| |..|..|
Mouse   347 VGQTHMG--SLFGAAGISPGLNGYEMNGEP 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9876	NP_611756.1	Homeobox	121..173	CDD:278475	36/51 (71%)
Alx4	NP_031468.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	68..133
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	171..206		11/36 (31%)
		Homeobox	206..258	CDD:278475	36/51 (71%)
		OAR	375..392	CDD:281777	79/225 (35%)
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	379..392
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010