DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9876 and Prrx2

DIOPT Version :9

Sequence 1:	NP_611756.1	Gene:	CG9876 / 37668	FlyBaseID:	FBgn0034821	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_001099209.1	Gene:	Prrx2 / 113931	RGDID:	1311471	Length:	248	Species:	Rattus norvegicus

Alignment Length:	185	Identity:	84/185 - (45%)
Similarity:	108/185 - (58%)	Gaps:	31/185 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 FSVDNIMEMKHDAYS--------KGKMAMELSSNFGPTGAGCGGADRPAPCSGNLPAGGGHHS-- 114
            |||.::::::..|.:        .|..|.|.::. .|:|...|  ...||..|.. |..||.|
  Rat    33 FSVSHLLDLEEVAAAGRRAAGPVPGPEAREGAAR-EPSGGSSG--SEAAPQDGEC-AAPGHGSAT 93

  Fly   115 ---RKPRRNRTTFSSAQLTALEKVFERTHYPDAFVREELATKVHLSEARVQVWFQNRRAKFRRNE 176
               :|.|||||||:|:||.|||:|||||||||||||||||.:|:|||||||||||||||||||||
  Rat    94 KRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNE 158

  Fly   177 RSV---GSRTLLDTAPQ-------LVPAPISNNMHKYANMPHPHPQ---PPPPPG 218
            |::   .|.:||.:..|       :.|.|.:.: ..|.:.|...|.   ||..||
  Rat   159 RAMLATRSASLLKSYGQEAAIEQPVAPRPTTLS-PDYLSWPASSPYSSVPPYSPG 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9876	NP_611756.1	Homeobox	121..173	CDD:278475	44/51 (86%)
Prrx2	NP_001099209.1	Homeobox	104..156	CDD:395001	44/51 (86%)
		COG5576	<110..214	CDD:227863	58/104 (56%)
		OAR	222..238	CDD:397759
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	105	1.000	Domainoid score	I6517
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4636
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	1	1.000	-	-		otm45609
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3194
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.960