Protein Alignment CG9876 and CDX1

DIOPT Version :10

• Sequence 1: NP_611756.1
• Gene: CG9876 / 37668
• FlyBaseID: FBgn0034821
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_001795.2
• Gene: CDX1 / 1044
• HGNCID: 1805
• Length: 265
• Species: Homo sapiens
• Alignment Length: 184
• Identity: 52/184 - (28%)
• Similarity: 70/184 - (38%)
• Gaps: 55/184 - (29%)

  Fly    76 GKMAMELSSNFGPTGAGCGGADRPAP---CSGNLPAGGGHHSRKPR---RNRTTFSSAQLTALEK 134
            |.:|..|.   ||......||.||.|   ...::.||||..|.|.|   :.|..::..|...|||
Human   110 GLLAQPLG---GPGTPSSPGAQRPTPYEWMRRSVAAGGGGGSGKTRTKDKYRVVYTDHQRLELEK 171

  Fly   135 VFERTHYPDAFVREELATKVHLSEARVQVWFQNRRAKFRRNERSVGSRTLLDTAPQLVPAPISNN 199
            .|..:.|.....:.|||..:.|:|.:|::||||||||    ||.|..:
Human   172 EFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAK----ERKVNKK----------------- 215

  Fly   200 MHKYANMPHPHPQPPPPPGAYALNFGPLELRSCQNYTNCYGGFGSSGASGSGVC 253
                   .....|||.||.|:.:...|                  :|.|..|:|
Human   216 -------KQQQQQPPQPPMAHDITATP------------------AGPSLGGLC 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9876	NP_611756.1	Homeodomain	118..174	CDD:459649	22/58 (38%)
CDX1	NP_001795.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	9..153		16/45 (36%)
		Caudal_act	13..142	CDD:461413	10/34 (29%)
		Homeodomain	156..211	CDD:459649	22/58 (38%)
		Interaction with DNA. /evidence=ECO:0000305|PubMed:28473536	157..178		6/20 (30%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000305|PubMed:28473536	196..207		6/10 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	207..265		16/84 (19%)