DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9876 and prrx1

DIOPT Version :9

Sequence 1:	NP_611756.1	Gene:	CG9876 / 37668	FlyBaseID:	FBgn0034821	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	XP_004913839.1	Gene:	prrx1 / 100494324	XenbaseID:	XB-GENE-484663	Length:	248	Species:	Xenopus tropicalis

Alignment Length:	264	Identity:	97/264 - (36%)
Similarity:	128/264 - (48%)	Gaps:	64/264 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SSHQSHNLESEDKLEDREESG-----RNLDKIHRFSVDNIMEMKHDAYSKGKMAMELSSNFGPTG 90
            ||:..|.|:.:..|..|.||.     .||.....|||.::::::......|..|.:
Frog     3 SSYNHHVLDRQGPLGSRLESPITASLDNLQAKKNFSVSHLLDLEEAGEMVGAQAED--------- 58

  Fly    91 AGCGGADRPAPCSGNLPAGGG-------------HHSRKPRRNRTTFSSAQLTALEKVFERTHYP 142
             |.|.|.|....|..|.:|..             ...||.|||||||:|:||.|||:||||||||
Frog    59 -GSGEAGRSLLESPGLTSGSDTPQQENEQMNAEQKKKRKQRRNRTTFNSSQLQALERVFERTHYP 122

  Fly   143 DAFVREELATKVHLSEARVQVWFQNRRAKFRRNERSV---GSRTLLDTAPQLVPA---PISNNMH 201
            ||||||:||.:|:|:||||||||||||||||||||::   .:.:||.:....|.|   ||.
Frog   123 DAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYAGDVTAVEQPIV---- 183

  Fly   202 KYANMPHPHPQPPPPPGAYALNFGPLELRSCQNYTNCYGGFGSSGASGSGVCSFFGATNYCVAAN 266
                     |:|.|.|..| |::|     :...|        |:.|:.|..|:   .||.....|
Frog   184 ---------PRPAPRPNEY-LSWG-----TASPY--------SAMATYSSTCA---NTNPAQGMN 222

  Fly   267 YAKN 270
            .|.:
Frog   223 MANS 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9876	NP_611756.1	Homeobox	121..173	CDD:278475	42/51 (82%)
prrx1	XP_004913839.1	Homeobox	102..154	CDD:365835	42/51 (82%)
prrx1	XP_004913839.1	OAR	221..238	CDD:367680	2/6 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I6720
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	122	1.000	Inparanoid score	I4597
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	1	1.000	-	-		otm48701
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5800
SonicParanoid	1	1.000	-	-		X3194
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.990