DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art7 and Bud23

DIOPT Version :9

Sequence 1:	NP_611753.4	Gene:	Art7 / 37664	FlyBaseID:	FBgn0034817	Length:	690	Species:	Drosophila melanogaster
Sequence 2:	XP_030110611.1	Gene:	Bud23 / 66138	MGIID:	1913388	Length:	300	Species:	Mus musculus

Alignment Length:	286	Identity:	54/286 - (18%)
Similarity:	97/286 - (33%)	Gaps:	84/286 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 HDVQLSQLPSSAFRP-LTDPVEIFQFDFQRKQEREKQRSQLLKLQSKQ-PGAAELV-------FY 277
            |.::::   |.:.|| .:.|.|:| :| |.:..:..:.|:::.:|:|. ..|.||:       .|
Mouse    16 HTIEMA---SRSRRPEHSGPPELF-YD-QNEARKYVRNSRMIDIQTKMTERALELLCLPEGQPSY 75

  Fly   278 WWDIQLDD--DGEILLSCAPYWA----HPQLKELAAEKAKDHPL-----PNVVPWRDHWMQAIYY 331
            ..||....  .|:.:.....||.    .|.:.:.|.::..:..|     ...||:|.........
Mouse    76 LLDIGCGSGLSGDYISEEGHYWVGIDISPAMLDAALDRDTEGDLLLGDMGQGVPFRPGSFDGCIS 140

  Fly   332 IPKPLQLLEAGKSFHLSCHHDEYSLWFDAREEAPTKSVRRHTCTCDLHMTYSRSRIGQLNQSPRN 396
            |.....|..|.|                 :.:.|.:  |.:.....|:....|.....|...|.|
Mouse   141 ISAVQWLCNANK-----------------KSDVPAR--RLYCFFSSLYSALVRGARAVLQLYPEN 186

  Fly   397 KRYLRYL-----------------EESIEAEKSNVLVLGNGCLLGLASSAL------------GA 432
            ...|..:                 ..|.:|:|..:      ||....|::|            .:
Mouse   187 SEQLELITTQATRAGFTGGVVVDFPNSAKAKKFYL------CLFSGPSTSLPKGLTESQDADQAS 245

  Fly   433 ASVLLHE--PHRFSRRLIESIVKHNQ 456
            .|:...|  ||:.:||   .:||.::
Mouse   246 ESMFTSERAPHKKARR---DLVKKSR 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art7	NP_611753.4	AdoMet_MTases	36..>186	CDD:302624
Bud23	XP_030110611.1	UbiG	37..>110	CDD:225137	15/73 (21%)
		Methyltransf_11	77..>147	CDD:369777	12/69 (17%)
		WBS_methylT	223..298	CDD:372208	11/49 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900