DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art7 and bud23

DIOPT Version :9

Sequence 1:	NP_611753.4	Gene:	Art7 / 37664	FlyBaseID:	FBgn0034817	Length:	690	Species:	Drosophila melanogaster
Sequence 2:	NP_001076348.1	Gene:	bud23 / 572367	ZFINID:	ZDB-GENE-070410-68	Length:	282	Species:	Danio rerio

Alignment Length:	195	Identity:	39/195 - (20%)
Similarity:	67/195 - (34%)	Gaps:	41/195 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 LPSSAFRP-LTDPVEIFQFDFQRKQEREKQRSQLLKLQSK-QPGAAELV-------FYWWDIQLD 284
            :.||..|| ...|.|:|..:.:.|  :..|.|:::::|:: ...|.||:       .|..|:...
Zfish     1 MSSSCRRPEHMAPPEVFYNEEEAK--KYSQNSRMIEIQTQMSERAVELLNLPEDQPCYLLDVGCG 63

  Fly   285 D--DGEILLSCAPYWAHPQLK----ELAAEKAKDHPL-----PNVVPWRDHWMQAIYYIPKPLQL 338
            .  .|:.|.....||....:.    ::|.|:..:..|     ...:|:|.........|.....|
Zfish    64 SGLSGDYLSEAGHYWVGVDISTAMLDVALEREVEGDLLLGDMGEGMPFRPGMFDGCISISALQWL 128

  Fly   339 LEAGKSFHLSCHHDEYSLWFDAREEAPTKSVRRHTCTCDLHMTYSRSRIGQLNQSPRNKRYLRYL 403
            ..|.|..|                 :|.|.:.|...|  |:.:.:|.........|.|...|..:
Zfish   129 CNADKKTH-----------------SPPKRLYRFFST--LYSSLARGARAVFQIYPENSEQLELI 174

Fly 404 403
Zfish 175 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art7	NP_611753.4	AdoMet_MTases	36..>186	CDD:302624
bud23	NP_001076348.1	Methyltransf_11	58..133	CDD:285453	13/74 (18%)
bud23	NP_001076348.1	WBS_methylT	204..280	CDD:289366
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900