DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art7 and carm1

DIOPT Version :9

Sequence 1:	NP_611753.4	Gene:	Art7 / 37664	FlyBaseID:	FBgn0034817	Length:	690	Species:	Drosophila melanogaster
Sequence 2:	NP_001003645.1	Gene:	carm1 / 445251	ZFINID:	ZDB-GENE-040724-77	Length:	588	Species:	Danio rerio

Alignment Length:	368	Identity:	82/368 - (22%)
Similarity:	139/368 - (37%)	Gaps:	92/368 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SCFSHVMNPITGQNS----WQERGDD---------YDYHLEVANAGFGDMLHDWERNQKYFAALR 53
            |.|.:::....||..    :.:|.::         |.|..:..|     |:.|:.|...|..|:.
Zfish    92 SSFYNLLKICRGQKGDRSVFSDRTEESSAVQYFQFYGYLSQQQN-----MMQDYVRTGTYQRAIL 151

  Fly    54 KTIAGMREAGREVHVLDIGTGTGILSMMALAAGADSVTACEAFLPMANCAEKILAANGAGDKVRL 118
            :.....::.    .|||:|.|:||||..|..|||..|.|.|| ..||..||.::.:|...::|.:
Zfish   152 QNHTDFKDK----VVLDVGCGSGILSFFAAQAGARKVYAVEA-STMAQHAEVLVNSNRLSERVVV 211

  Fly   119 IRKRSTEIQVGEDMPRKANLLVAELLDTELIGEGAIGIYNHAHAELLTEDALCIPARARCYAQVA 183
            |..:..|:    .:|.:.:::::|.:...|..|..:..|.|| .:.|.......|.    ...|.
Zfish   212 IPGKVEEV----SLPEQVDIIISEPMGYMLFNERMLESYLHA-KKFLKPSGKMFPT----IGDVH 267

  Fly   184 QSPLAAQWNSLK--TIANLDGEPLLHPPEQLKSCQGEAALHDVQLSQLPSSA----FR-PLTDPV 241
            .:|...:...::  |.||...:|               :.|.|.||.|..:|    || |:.|..
Zfish   268 LAPFTDEQLYMEQFTKANFWYQP---------------SFHGVDLSALRGAAVDEYFRQPIVDTF 317

  Fly   242 EI---------FQFDFQRKQEREKQRSQL-LKLQSKQPGAAELVFYWWDIQLDDDGEIL---LSC 293
            :|         :..:|...:|.:..:.:: .|......|....:.:|:|:..  .|.::   ||.
Zfish   318 DIRILMAKSVKYTVNFLEAKEEDLYKIEIPFKFHMMHSGLVHGLAFWFDVAF--IGSVMTVWLST 380

  Fly   294 APYWAHPQLKELAAEKAKDHPLPNVVPWRDHWMQAIYYIPKPL 336
            ||                ..||       .||.|....:..||
Zfish   381 AP----------------TEPL-------THWYQVRCLLQSPL 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art7	NP_611753.4	AdoMet_MTases	36..>186	CDD:302624	40/149 (27%)
carm1	NP_001003645.1	CARM1	8..112	CDD:288395	4/19 (21%)
		PRMT5	<146..409	CDD:282971	71/309 (23%)
		AdoMet_MTases	162..263	CDD:100107	34/110 (31%)
		Transactivation domain. /evidence=ECO:0000250	473..588
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810