DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art7 and Art4

DIOPT Version :9

Sequence 1:	NP_611753.4	Gene:	Art7 / 37664	FlyBaseID:	FBgn0034817	Length:	690	Species:	Drosophila melanogaster
Sequence 2:	NP_001262445.1	Gene:	Art4 / 41219	FlyBaseID:	FBgn0037770	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	472	Identity:	104/472 - (22%)
Similarity:	175/472 - (37%)	Gaps:	109/472 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VMNPITGQNSWQERGDDYDYHLEVANAGFGDMLHDWERNQKYFAALRKTIAGMREAGREVHVLDI 71
            |.:..|.::|..:....|.|..:..|     |:.|:.|...|    ::.|.|.....::..|||:
  Fly   131 VFSQRTEESSASQYFQFYGYLSQQQN-----MMQDYVRTSTY----QRAILGNAVDFQDKIVLDV 186

  Fly    72 GTGTGILSMMALAAGADSVTACEAFLPMANCAEKILAANGAGDKVRLIRKRSTEIQVGEDMPRKA 136
            |.|:||||..|:.|||..|.|.|| ..||..|::::.:|....|:.:|..:..||    ::|.|.
  Fly   187 GAGSGILSFFAVQAGAAKVYAIEA-SNMAQYAQQLVESNNVQHKISVIPGKIEEI----ELPEKV 246

  Fly   137 NLLVAELLDTELIGEGAIGIYNHAHAELLTEDALCIPARARCYAQVAQSPLAAQWNSLKTIANLD 201
            :::::|.:...|..|..:..|.||...|..:..: .|.....:                 ||...
  Fly   247 DVIISEPMGYMLYNERMLETYLHARKWLKPQGKM-YPTHGDLH-----------------IAPFS 293

  Fly   202 GEPLLHPPEQLKSCQGEAALHDVQLSQLPSSAFR-----PLTDPVEI---------FQFDFQRKQ 252
            .|.|........:...::|.|.|.|:.|.....:     |:.|..:|         ...||...:
  Fly   294 DESLYSEQYNKANFWYQSAFHGVDLTTLHKEGMKEYFRQPIVDTFDIRICMAKSVRHVCDFLNDK 358

  Fly   253 EREKQRSQL-LKLQSKQPGAAELVFYWWDIQLDDDGE-ILLSCAPYWAHPQLKELAAEKAKDHPL 315
            |.:.....: |:....|.|....:.:|:|::.....: :.||.:|                ..||
  Fly   359 EDDLHLISIPLEFHILQTGICHGLAFWFDVEFSGSSQNVWLSTSP----------------TAPL 407

  Fly   316 PNVVPWRDHWMQAIYYIPKPL-----------QLLEAGKSFHLSCHHDEYSLWFDAREEAPTKSV 369
                   .||.|....:|.|:           .||||.:       ...|.:..|...|....|
  Fly   408 -------THWYQVRCLLPMPIFIKQGQTLTGRVLLEANR-------RQSYDVTIDLHIEGTLIS- 457

  Fly   370 RRHTCTCDLHMTYSR-------SRIGQLNQSPRNKRYLRYLEESIEAEKSNVLVLGNGCLLGLAS 427
              .:.|.||...|.|       :..|...||| :::|...::.......|::|   ||   |::.
  Fly   458 --SSNTLDLKNPYFRYTGAPVQAPPGTSTQSP-SEQYWTQVDTQGSRNSSSML---NG---GISV 513

  Fly   428 SALGAASVLLH---EPH 441
            :.:|....:.|   .||
  Fly   514 NGIGEGMDITHGLMHPH 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art7	NP_611753.4	AdoMet_MTases	36..>186	CDD:302624	41/149 (28%)
Art4	NP_001262445.1	PH-like	24..134	CDD:302622	1/2 (50%)
		PRMT5	53..430	CDD:282971	77/353 (22%)
		AdoMet_MTases	183..281	CDD:100107	34/103 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440101
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11006
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840