DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Art7 and Art8

DIOPT Version :9

Sequence 1:NP_611753.4 Gene:Art7 / 37664 FlyBaseID:FBgn0034817 Length:690 Species:Drosophila melanogaster
Sequence 2:NP_609478.1 Gene:Art8 / 34528 FlyBaseID:FBgn0032329 Length:341 Species:Drosophila melanogaster


Alignment Length:394 Identity:92/394 - (23%)
Similarity:149/394 - (37%) Gaps:108/394 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 DDYDYHLEVANAGFGDMLHDWERNQKYFAALRKTIAGMREAGREVHVLDIGTGTGILSMMALAAG 86
            |:|: :||:...    ||.|..|.:.|:.|    |.|.::..::..|:|:|.||||||.....||
  Fly     7 DEYE-NLEIHEL----MLKDRPRQEAYYNA----ILGNKDLFKDKIVMDVGAGTGILSAFCAKAG 62

  Fly    87 ADSVTACEAFLPMANCAEKI----LAANGAGDKVRLIRKRSTEIQVGEDMPRKANLLVAELLDTE 147
            |..|.|.||    :|.|.|:    :..||..:.|::|:.|..|..:..: ..|.:::|:|.:...
  Fly    63 ARLVYAVEA----SNVATKVALDLIEDNGLTNVVKVIQSRVEEFVLPAE-AEKVDIIVSEWMGFY 122

  Fly   148 LIGEGAIGIYNHAHAELLTEDALCIPARARCYAQVAQSP-LAAQWNSLKTIANLDGEPLLHPPEQ 211
            |:.||.:.....|..:.|.|..|..|:....:......| |...|:      |:||         
  Fly   123 LLHEGMLDSVLLARDKFLKEGGLLFPSECTIFVAPCSVPSLFDDWH------NVDG--------- 172

  Fly   212 LKSCQGEAALHDVQLSQLPSSAFRPLTDPVEIFQFDFQRKQEREK-QRSQLLKLQSKQPGAAELV 275
                                           |....|.||...:| .|.::.:|..:......:|
  Fly   173 -------------------------------IKMDTFARKLRTQKSSRPEITQLNPQDLLHEGVV 206

  Fly   276 FYWWDIQLDDDGEILLSCAPYWAHPQLKE-LAAEKAKDHPLPNVVPWRD---------------- 323
            |:|.:: ||.:...|.|.       |.|| :.|:||.:|  .....|.|                
  Fly   207 FHWMNL-LDVEASDLDSI-------QFKEVITAQKAGNH--QGFCIWFDVQFPGEDFVLSTSPLS 261

  Fly   324 ---HWMQAIYYIP-KPLQLLEAGK--SFHLSCHHD-----EYSLWFDAREEAPTKSVRRHTCTCD 377
               ||.|.:..:| :..:.||...  :|.::....     :|:|..|..:    .:...|...|.
  Fly   262 PPTHWKQCVVVLPEESCENLEEKSPIAFQITMKRSAADMRKYNLEVDLLD----PNTEEHPVPCS 322

  Fly   378 LHMT 381
            .|||
  Fly   323 CHMT 326

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Art7NP_611753.4 AdoMet_MTases 36..>186 CDD:302624 44/153 (29%)
Art8NP_609478.1 SmtA 1..244 CDD:223574 75/306 (25%)
Methyltransf_18 40..147 CDD:289607 35/111 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45440094
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0500
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR11006
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
43.840

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