Protein Alignment Art7 and Prmt7

DIOPT Version :10

• Sequence 1: NP_611753.4
• Gene: Art7 / 37664
• FlyBaseID: FBgn0034817
• Length: 690
• Species: Drosophila melanogaster
• Sequence 2: NP_663379.1
• Gene: Prmt7 / 214572
• MGIID: 2384879
• Length: 692
• Species: Mus musculus
• Alignment Length: 715
• Identity: 262/715 - (36%)
• Similarity: 392/715 - (54%)
• Gaps: 60/715 - (8%)

  Fly     1 MSCFSHVMNPITGQNSWQERGDDYDYHLEVANAGFGDMLHDWERNQKYFAALRKTIAGMREAGRE 65
            |..|....||.||...|.|..:.||||.|:|.:.:.|||||.:||.||:..:|..::.:::.|::
Mouse     1 MKVFCGRANPTTGSLEWLEEDEHYDYHQEIARSSYADMLHDKDRNIKYYQGIRAAVSRVKDRGQK 65

  Fly    66 VHVLDIGTGTGILSMMALAAGADSVTACEAFLPMANCAEKILAANGAGDKVRLIRKRSTEIQVGE 130
            ..|||||||||:|||||:.||||...|.|.|.|||..|.||:..||..||:::|.|.|||:.||.
Mouse    66 ALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMAEAAVKIVERNGFSDKIKVINKHSTEVTVGP 130

  Fly   131 --DMPRKANLLVAELLDTELIGEGAIGIYNHAHAELLTEDALCIPARARCYAQVAQSPLAAQWNS 193
              |:|.:||:|:.||.|||||||||:..|.|||..|:.||...:|.||..|||:.:|.....||.
Mouse   131 DGDLPCRANILITELFDTELIGEGALPSYEHAHKHLVQEDCEAVPHRATVYAQLVESRRMWSWNK 195

  Fly   194 L---KTIANLDGEPLLHPPEQLKSCQGEAALHDVQLSQLPSSAFRPLTDPVEIFQFDFQRKQERE 255
            |   :...:| ||.::.||.:|:.|.|..::.|:||:|:..:.|..|:|.:.:|..||      .
Mouse   196 LFPVRVRTSL-GEQVIVPPSELERCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSVDF------S 253

  Fly   256 KQRSQLLKLQSKQ-----PGAAELVFYWWDIQLDDDGEILLSCAPYWAHPQLKELAAEKAKDHPL 315
            ||.|......|:|     .|.|::|..||||::|.:|:|..:.||:||....:||
Mouse   254 KQVSSSAACHSRQFVPLASGQAQVVLSWWDIEMDPEGKIKCTMAPFWAQTDPQEL---------- 308

  Fly   316 PNVVPWRDHWMQAIYYIPKPLQLLEAGKSFHLSCHHDEYSLWFDAREEAPTKSVR----RHTCTC 376
                .|||||||.:|::|:...::: |....|..|||:|.:|:..:..:|.::..    |..|.|
Mouse   309 ----QWRDHWMQCVYFLPQEEPVVQ-GSPRCLVAHHDDYCVWYSLQRTSPDENDSAYQVRPVCDC 368

  Fly   377 DLHMTYSRSRIGQLNQSPRNKRYLRYLEESIEAEKSNVLVLGNGCLLGLASSALGAASVLLHEPH 441
            ..|:.::|.|.|::|...|...|.:.| .::....|..|.:.:|.||.:.:..|||..|...|..
Mouse   369 QAHLLWNRPRFGEINDQDRTDHYAQAL-RTVLLPGSVCLCVSDGSLLSMLAHHLGAEQVFTVESS 432

  Fly   442 RFSRRLIESIVKHNQLKN-VQFLDK------VEELEDSRLAALTHIFAEPYFLNAILPWDNFYFG 499
            ..|.||::.|.|.|.|:: :..::|      ..:||..:::.|   ..||:|..::|||.|.||.
Mouse   433 VASYRLMKRIFKVNHLEDKISVINKRPELLTAADLEGKKVSLL---LGEPFFTTSLLPWHNLYFW 494

  Fly   500 TLLTKIKDRLPEGVKISPCSARIYALPVEFLDLHKIRAPVGSCEGFDLRLFDEMVERSAEQAVSL 564
            .:.|.:...|..|..:.|.:|.::|:.|||.||.:||:|.|.|||||:.:.|:|::.|.:...|.
Mouse   495 YVRTSVDQHLAPGAVVMPQAASLHAVIVEFRDLWRIRSPCGDCEGFDVHIMDDMIKHSLDFRESR 559

  Fly   565 -VEAQPLWEYPCRALSEPQEVLSVDFSN--FGQEHSLKGSIELKHPRICNGVALWVDWQLVEDNS 626
             .|..||||||||:||:|||:|:.||..  ..|....||::||..|...:|..||:::||    :
Mouse   560 EAEPHPLWEYPCRSLSKPQEILTFDFQQPIPQQPMQSKGTMELTRPGKSHGAVLWMEYQL----T 620

  Fly   627 PRSIVSSGPSEPVVPGEFVKWDMFVRQGVHF------PRRPKEAITHLEWSTVFKPLLGELTFSF 685
            |.|.:|:|...|........|:...:|.|:|      .|.|......:.:...|.||.|::|..|
Mouse   621 PDSTISTGLINPAEDKGDCCWNPHCKQAVYFLSTTLDLRVPLNGPRSVSYVVEFHPLTGDITMEF 685

  Fly   686  685
            Mouse   686  685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Art7	NP_611753.4	COG4076	38..>189	CDD:443253	78/152 (51%)
Prmt7	NP_663379.1	COG4076	38..>188	CDD:443253	77/149 (52%)
		COG4076	382..>523	CDD:443253	40/144 (28%)