DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art7 and F49C12.10

DIOPT Version :9

Sequence 1:	NP_611753.4	Gene:	Art7 / 37664	FlyBaseID:	FBgn0034817	Length:	690	Species:	Drosophila melanogaster
Sequence 2:	NP_501633.1	Gene:	F49C12.10 / 177754	WormBaseID:	WBGene00009879	Length:	275	Species:	Caenorhabditis elegans

Alignment Length:	236	Identity:	46/236 - (19%)
Similarity:	84/236 - (35%)	Gaps:	78/236 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 VQLSQLPSSAFRPLTDPVEIFQFDFQRKQEREKQRSQLL---KLQSKQPGAAELVFYWWDIQLDD 285
            :.|...||||  |....:.:|..|.....|.|..|:.:.   |..|..|...    |:      :
Worm    40 MNLGYWPSSA--PQYAKMRMFMEDLGDLDEYESDRAHIYLYEKALSMHPNYP----YF------E 92

  Fly   286 DGEIL-LSCA--------PYWAHPQLKELAAEKAKDHPLPNVV-------PWRDHWMQAIYYIPK 334
            ..||| :||.        ..|..|....:..:|.....:.|:|       |:.|:....:..:
Worm    93 QFEILEVSCGQGYSLDWIEKWHGPTKCIIGCDKVVTRNMNNIVYGDALDLPFADNSFDFVLNV-- 155

  Fly   335 PLQLLEAGKSFHLSCHHDEYSLWF----------------DAR--------EEAPTKS--VRRH- 372
                    ::.||   :.:|.|:|                |.|        :|..|.:  |::|
Worm   156 --------EAAHL---YSDYKLFFKEGSRVLRSGGAFCYMDIRYPHEAKQIQETATAAGFVKKHF 209

  Fly   373 -TCTCDL--HMTYSRSRIGQ-LNQSPRNKRYLRYLEESIEA 409
             .||.::  .:.||..:..: |.::|   .::::.:.|:.|
Worm   210 EFCTDEVVEGLKYSARKYDRLLEKAP---FFVKFFKNSLRA 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art7	NP_611753.4	AdoMet_MTases	36..>186	CDD:302624
F49C12.10	NP_501633.1	Methyltransf_11	97..182	CDD:369777	15/97 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900