Protein Alignment CG3085 and Tekt2

DIOPT Version :10

• Sequence 1: NP_611752.1
• Gene: CG3085 / 37663
• FlyBaseID: FBgn0034816
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_036032.2
• Gene: Tekt2 / 24084
• MGIID: 1346335
• Length: 430
• Species: Mus musculus
• Alignment Length: 1177
• Identity: 203/1177 - (17%)
• Similarity: 346/1177 - (29%)
• Gaps: 491/1177 - (41%)

  Fly     3 ARTTNSSRQGDLAAIRKILENETGGAL--CP-------SC-QMPFDKGKKRKLIDACGHERCYSC 57
            |...|:|:.|       |:|   |||:  ||       || |:||||
Mouse    77 APKANTSQPG-------IVE---GGAVYYCPWPASDPDSCRQIPFDK------------------ 113

  Fly    58 MFRNEACPHCQAQKEPNQPGHPPQHHPASRMHGYGSSNHLMSPLGSPQPQNRSQMRTNGHFSSIY 122
                                               ::|.::...|:.:|   .:.:::..|.:..
Mouse   114 -----------------------------------ANNRMIKVNGTREP---LEFKSHQWFGATV 140

  Fly   123 QKQRGR---SAKIFPYKGYGSTGNTTTASRCTDFGSPFWSISYQVKILIISFRSWC--------- 175
            :..:|:   .|.::.::      ....:|.....|:.:        :.:.:|.::.
Mouse   141 RTHKGKVVACAPLYQWR------TVKVSSEMDPVGTCY--------VAVQNFSAYAEYSPCRTNN 191

  Fly   176 GDGSGGG---AGV--------TPVLPAGGSLFSPSDIL--GTAE---RYKLKDRPPKCPPGGKTE 224
            .|..|.|   ||.        |.|:...||.:....::  |.||   .|.||....|..  |:.:
Mouse   192 PDPEGQGFCQAGFSVDFTKEGTLVVGGPGSFYWQGQVITAGVAEILNGYSLKTILRKVQ--GEKQ 254

  Fly   225 SHYASIT---------------TGST------GVAGSTHHQQPGYGMMKPLQQRSALNSSSEITS 268
            :..||.|               ||.:      ||....|:    :|.:             .:.:
Mouse   255 TVAASDTYDDSYLGYSVAVGEFTGDSEQELVAGVPRGAHN----FGYV-------------TVIN 302

  Fly   269 STCATPPQNRRRLFSPKNLRSPFGYRRS----NGNAADNSTLSGLASLLNPATFHRATTAAASKI 329
            :|..|..||    |:.:.:.|.|||..:    ||:..|:..:..      |....|...:...::
Mouse   303 ATNLTFIQN----FTGEQMASYFGYTIAVTDLNGDGLDDVLVGA------PLYMDREFESKPREV 357

  Fly   330 SR---------------------------SMALRTTGGLSRDG------GGGSGGSSSGG----- 356
            .|                           ..|:...|.:::||      |....|...||
Mouse   358 GRVYLYLQEDVLLFSPPITLTGMHLFGRYGSAIAPLGDINQDGYLDVAIGAPFAGEDRGGRVFIY 422

  Fly   357 VGGGSGFNLLASH---------GPPMN-GISKRQRNANDGHKFHRLSLGSSASMVFG--KIKSLW 409
            .|..||..|.||.         |.|.. |.:.|..:..|.:::..|.:|:     ||  |:.:..
Mouse   423 NGQKSGLMLQASQVLKGDWASSGIPAGFGFTLRGDSDLDNNQYPDLLVGA-----FGVSKVVAYR 482

  Fly   410 SAQATTVNAGLNQLAGMGSSSQSYDEGGNVKPLVMNGKSKSSQDELQVRLGFFLENNTRRNLRAP 474
            |....||:|.|                 .::|.::|.:.||                    .|.|
Mouse   483 SRPVVTVDAQL-----------------ILRPRILNPEDKS--------------------CRMP 510

  Fly   475 NQS----------CSSLTSANTSPVSTLTGSSEAD-------VSRVLQEPNPYHTGCESIG---- 518
            |..          |:.::.........|....:.|       |.|||...:..|...:.:.
Mouse   511 NSDIMVTCLSVNVCAKISGIGIPDYVALRMELQLDWLKQRGAVKRVLFMDSHQHQRSQQLVLGQG 575

  Fly   519 ----------------------SMMSIS-----EQSNASSS----PVSRRHSVTTSQSGSNV--- 549
                                  |.:|::     :||:..:.    ||...:|.|.....:|:
Mouse   576 DRQHCHNYSVYLRDEAEFRDKLSPISVTLNYSLDQSSPPAGLQLRPVLDHYSKTFHHEQANILLD 640

  Fly   550 --------------------------DDLLAFKSRRTTVRRSARSGQIKGPIDPKIRFAQYRQQH 588
                                      |:||............|...::...:.|:   |.|....
Mouse   641 CGEDNMCIPDLKLSAKMDRTELIIGDDNLLMLTINAANEGEGAYEAELHVTLPPE---ADYIGVE 702

  Fly   589 QQQQQLQQQLTLKPLFFEVPTHEP---------NP------LFVGRHWLVRELATAIQSTDSPGV 638
            ::::.||:      |..|..|...         ||      |.||..:.|..|..|..:......
Mouse   703 RRREDLQR------LNCEHRTENDTRIVVCDLGNPMVADTNLSVGLRFSVARLEDAPPTIGFEVQ 761

  Fly   639 LLSGNLGTGKTA---LLLQLV---EYSCFG--------------RRKELPIQENDGIYCQINVAH 683
            :.|.|....::.   |.|.:|   |....|              ..||.|::|
Mouse   762 IHSSNKDNSRSVPVNLTLSIVARAEVEIRGVSHPAQVVLPFPRWEPKEKPVRE------------ 814

  Fly   684 DRLRTLASHVVAYHFCQADNNSTCLIPDFVHSLAAQLCQAPQLAAYHEFLLGEHALQHALSV--- 745
            |.:.....|:...|     |...       .|::..:.:....:.|.|    ||.| :||.|
Mouse   815 DEVGPQVQHIYELH-----NKGP-------SSISRTVLEVGWPSRYRE----EHLL-YALQVITD 862

  Fly   746 --KECIANP-------ERAMTMGILEPLAALRRTGKIPAK---------------NCVILVDALC 786
              ..|..|.       |.:......|.|..||.:..:..:               ||..:...:.
Mouse   863 GPVHCSTNSSLNPLELETSTLQDTPELLGFLRNSSGVTRRRRSVSIGQSYNSKTLNCSNINCLMV 927

  Fly   787 EAEYHRPDHGDTVA----------SFLQRMSEHFPPWLKVIATIRTQMLEFCKGLPYTKMSLDSW 841
            |....|.|.|.:..          :||||.::|:    .:.:|:..|:    ..:||
Mouse   928 ECVVDRLDRGQSAVIKFRSRLWAYTFLQRRNDHY----TLNSTVSFQV----TAMPY-------- 976

  Fly   842 ATNEMLQKDILEYITFRINQSQSIQHNVAGGKEIINTSAHFKFAQHL----LALSKGSFLFAKLT 902
                .::.:.|.      .||:||      |..::.......||..|    ||:..|..:.|.|:
Mouse   977 ----RIKAETLP------RQSKSI------GTFVVWAIPDVSFAIPLWVIILAILLGLLVLAVLS 1025

  Fly   903 LDLIERG 909
            |.:.:.|
Mouse  1026 LAMWKCG 1032

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3085	NP_611752.1	Tektin	21..401	CDD:460827	84/490 (17%)
Tekt2	NP_036032.2	Tektin	17..398	CDD:460827	70/429 (16%)