DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9890 and ztf-7

DIOPT Version :9

Sequence 1:	NP_611750.1	Gene:	CG9890 / 37659	FlyBaseID:	FBgn0034814	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_505526.1	Gene:	ztf-7 / 179375	WormBaseID:	WBGene00009772	Length:	614	Species:	Caenorhabditis elegans

Alignment Length:	447	Identity:	139/447 - (31%)
Similarity:	220/447 - (49%)	Gaps:	67/447 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CLKCDKVYIFPSDKDDCLAHLYMEHRLVIADVEDIALLEDYLQYWEKEFHTHEFEQYCTTMFLDQ 97
            |:.|.:.:..|........||..||::|::::..|...:.|:::|.:.|.....::    :|...
Worm   190 CVSCLEFFDLPEQISGFADHLLKEHKIVVSEMNLIVDPKRYIEHWRQRFAKESIDK----IFPRI 250

  Fly    98 LP---DGKYAKNEKYYLLCDILPQDYELRRRLKEKRLSEALERHQFELTDRTFSKECLFCRAIIK 159
            .|   |..:.:.:.|||:.:.:.:|..||:||..:||.|||:..|.|..|.:|..:|:|||...:
Worm   251 EPSEGDSYFGETDYYYLMSENVAEDRSLRQRLAMRRLEEALQCQQREREDTSFQLQCIFCRYNAR 315

  Fly   160 GLRADYLDHLFDKHFLLVGKPEKLVYVDELLDHLEENLNRLMCLYCEKIFRDRPTLKEHMRKKGH 224
            |.|:..:.||:..|.|.:|.|:.||:|.|.::||:|.|:|..|:||||||.||.||.:||||:.|
Worm   316 GNRSKIIHHLYMIHHLNLGSPDNLVFVTEYIEHLKEKLHRNECIYCEKIFPDRNTLMDHMRKRNH 380

  Fly   225 KRINPNRREYDKYFLINYNRVPTAPTPRKQHLQKRRRETASVSTVADPETGSVDFDKHFAR-PDS 288
            :.:||....|||:::|||           ..|.||     .:..:|:      ||:..... .||
Worm   381 REVNPKNHYYDKFYIINY-----------LELGKR-----WLDVLAE------DFEDTMPTFQDS 423

  Fly   289 D-GEHDSDWSDWA---ADGEPSSIKCLFCHHLGDNFTALKKHMHEVHRLDFEKATS--SLNFYQR 347
            | .|.|::|.:|.   .|.:.:.:.||.|....||..:|.:||...|..|..|..|  .||.|||
Worm   424 DEEEEDNEWCEWQEDNLDADETRVVCLLCDASEDNAQSLLEHMKTTHEFDLLKNVSDDKLNSYQR 488

  Fly   348 VKVVNYLRRQMCLLRCVTCD-LQFDEEELLVEHMAQE---SHHGIGDKESWDKPEFFFPYIENDG 408
            ::::||:|:|.....|..|. .:|:....|.:|:.:.   ||  :.|...||..|...|...||.
Worm   489 LRLINYIRKQNYHADCWVCQKTEFENPLALQKHILEHKPLSH--LPDASIWDTEENLVPIFGNDH 551

  Fly   409 LL-------------CVLDDSGGD---------DPDVDTVR-IISED--SLAQINKD 440
            .|             |..||.|..         :...:||. :|:||  .|:::|:|
Worm   552 FLWMLESILEENEITCSSDDEGESEERFSKLVLESKSNTVEGVIAEDLPELSELNED 608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9890	NP_611750.1	zf-C2H2_2	151..238	CDD:289522	42/86 (49%)
CG9890	NP_611750.1	zf-C2H2_2	310..405	CDD:289522	33/100 (33%)
ztf-7	NP_505526.1	PTZ00108	<1..152	CDD:240271
		zf-C2H2_2	307..394	CDD:372293	42/86 (49%)
		C2H2 Zn finger	358..380	CDD:275371	15/21 (71%)
		zf-C2H2_2	449..>521	CDD:372293	25/71 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165250
Domainoid	1	1.000	109	1.000	Domainoid score	I4008
eggNOG	1	0.900	-	-		E1_KOG2482
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11087
Inparanoid	1	1.050	212	1.000	Inparanoid score	I2362
Isobase	1	0.950	-	0	Normalized mean entropy	S6300
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1498904at2759
OrthoFinder	1	1.000	-	-		FOG0005654
OrthoInspector	1	1.000	-	-		oto19927
orthoMCL	1	0.900	-	-		OOG6_104708
Panther	1	1.100	-	-	LDO	PTHR13267
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1950
SonicParanoid	1	1.000	-	-		X4057
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.780