DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fatp2 and FAA2

DIOPT Version :9

Sequence 1:	NP_995925.2	Gene:	Fatp2 / 37657	FlyBaseID:	FBgn0265187	Length:	714	Species:	Drosophila melanogaster
Sequence 2:	NP_010931.3	Gene:	FAA2 / 856734	SGDID:	S000000817	Length:	744	Species:	Saccharomyces cerevisiae

Alignment Length:	740	Identity:	156/740 - (21%)
Similarity:	265/740 - (35%)	Gaps:	176/740 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 TAISGLILYYQGPWYGVATLYAALISILLVRPGWRWF---YIAAVTTPRDTVALFAYIRVLLFIK 132
            |.::|   |.:|....:..||:.|  .|...|.::.|   ...|::.|.:.....:..|..|..:
Yeast    23 TRLAG---YTKGSDEYIEELYSQL--PLTSYPRYKTFLKKQAVAISNPDNEAGFSSIYRSSLSSE 82

  Fly   133 RQER---KNLNIG-DIFESNVARQPDKLAIVSE-----SQQW--TFR-----QVNEHSNRV---- 177
            ....   |||... |.|..:..|.|.:..:.|.     :..|  |||     .|::..:.:
Yeast    83 NLVSCVDKNLRTAYDHFMFSARRWPQRDCLGSRPIDKATGTWEETFRFESYSTVSKRCHNIGSGI 147

  Fly   178 ---ANVFHSHGYKKGD-VVGLLLENRAEFVATWLGLSKIGVITPLINTNLRGASLQHSITVGQCT 238
               .|.......:..| ||.:|..|..|::.|.|......:....:...|...:.::.:.:.:..
Yeast   148 LSLVNTKRKRPLEANDFVVAILSHNNPEWILTDLACQAYSLTNTALYETLGPNTSEYILNLTEAP 212

  Fly   239 ALIYGASFRSAVMDIAKDLPAHVGLYQFNDESNQEV-VASEGLSQGLAQQLNGLL---------E 293
            .||:..|....|:.:..|:.....|...::.::.|: :.:|.|.......||..:         :
Yeast   213 ILIFAKSNMYHVLKMVPDMKFVNTLVCMDELTHDELRMLNESLLPVKCNSLNEKITFFSLEQVEQ 277

  Fly   294 TAAKDKVAAGASRADHHDKLVYI-YTSGTTGLPKAAVITHSRYFFIAAGIHYTLGFKDQDVFYTP 357
            ....:|:.|.....   |.|..| :|||||||||...::|..   ||:||.:..     ..|..|
Yeast   278 VGCFNKIPAIPPTP---DSLYTISFTSGTTGLPKGVEMSHRN---IASGIAFAF-----STFRIP 331

  Fly   358 -------------LPLYHT-AGGVMSMGQALLFG--------STVVIR-----KKFSASGYFSDC 395
                         |||.|. ...|::...|:.||        .||::.     |.::.:......
Yeast   332 PDKRNQQLYDMCFLPLAHIFERMVIAYDLAIGFGIGFLHKPDPTVLVEDLKILKPYAVALVPRIL 396

  Fly   396 ARFQCTVGQYIGE------MARYILATPSAPHDRNHQVRMVFGNGLRPQIWPQFV-ERFGIRKVG 453
            .||:..:...:.:      :|..||.:.||        |.....|....|....| .|..|.|:.
Yeast   397 TRFEAGIKNALDKSTVQRNVANTILDSKSA--------RFTARGGPDKSIMNFLVYHRVLIDKIR 453

  Fly   454 EFYGATEGNANIMNNDSTVG--AIGFISRILP----QIYPISIIKADPHTGEPLRNSQGLC---- 508
            :..|.: .|:.|:...:.:.  .:.|:...|.    |.|.::...|.....||.....|.|
Yeast   454 DSLGLS-NNSFIITGSAPISKDTLLFLRSALDIGIRQGYGLTETFAGVCLSEPFEKDVGSCGAIG 517

  Fly   509 --ERC---EADEPGVFVGKIVRGNPCREFLG-------YVDQKASSKKVVHD-VFSKGDMAFISG 560
              ..|   ...|.|....|.::|.  .:..|       :.:...:||.|..| .||.||:|||.|
Yeast   518 ISAECRLKSVPEMGYHADKDLKGE--LQIRGPQVFERYFKNPNETSKAVDQDGWFSTGDVAFIDG 580

  Fly   561 DLLVADERGYLYFKDRTGDTFRW-KGENVSTSEVE-AQLSNLAGYKDVIVYGVSIPNTEGRAGMA 623
                   :|.:...||..:.|:. .||.::..::| ..||:......:.|:|
Yeast   581 -------KGRISVIDRVKNFFKLAHGEYIAPEKIENIYLSSCPYITQIFVFG------------- 625

  Fly   624 AIYDPTREVNVSQLGVELAKSLP-------------------NYARPQFLR--FLRKID-----L 662
               ||.:...|..:||::..:.|                   |..|.:.||  ||.||:     |
Yeast   626 ---DPLKTFLVGIVGVDVDAAQPILAAKHPEVKTWTKEVLVENLNRNKKLRKEFLNKINKCTDGL 687

  Fly   663 TGTFKLRKVELQQQGFNPEIIDDEL 687
            .|..||..:::   |..|..::|::
Yeast   688 QGFEKLHNIKV---GLEPLTLEDDV 709

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp2	NP_995925.2	PRK08279	115..714	CDD:236217	145/693 (21%)
Fatp2	NP_995925.2	AFD_class_I	163..680	CDD:302604	132/627 (21%)
FAA2	NP_010931.3	LC-FACS_euk	126..734	CDD:341250	133/632 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344295
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930