Protein Alignment Fatp2 and Slc27a2

DIOPT Version :10

• Sequence 1: NP_995925.2
• Gene: Fatp2 / 37657
• FlyBaseID: FBgn0265187
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_113924.2
• Gene: Slc27a2 / 65192
• RGDID: 71103
• Length: 620
• Species: Rattus norvegicus
• Alignment Length: 669
• Identity: 245/669 - (36%)
• Similarity: 351/669 - (52%)
• Gaps: 71/669 - (10%)

  Fly    66 LAPVL-TAISGLILYYQGPWYGVATLYAALISILL--VRPGWRWFYIAAVTTPRDTVALFAYIRV 127
            :.||| |.::||:|        :..|.......||  ||     |::......|...:.
  Rat     1 MLPVLYTGLAGLLL--------LPLLLTCCCPYLLQDVR-----FFLQLANMARQVRSY------ 46

  Fly   128 LLFIKRQERKNLNIGDIFESNVARQPDKLAIVSESQQWTFRQVNEHSNRVANVFHSH-GYKKGDV 191
                 ||.|....|..:|.....:.|.|..::...:..|:.||:..||:||...|.| |.::||.
  Rat    47 -----RQRRPVRTILHVFLEQARKTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDC 106

  Fly   192 VGLLLENRAEFVATWLGLSKIGVITPLINTNLRGASLQHSITVGQCTALIYGASFRSAVMDIAKD 256
            |.|.:.|...:|..||||.|:|.....:|.|:|..||.|..   ||..              ||.
  Rat   107 VALFMGNEPAYVWLWLGLLKLGCPMACLNYNIRAKSLLHCF---QCCG--------------AKV 154

  Fly   257 LPAHVGLYQFNDESNQEVVAS---EGLS---QGLAQQLNGLLETAAK-DKVAAG------ASRAD 308
            |.|...|:    |:.:||:.:   ||:|   .......||:.....| |.|:|.      .|...
  Rat   155 LLASPELH----EAVEEVLPTLKKEGMSVFYVSRTSNTNGVDTVLDKVDGVSADPIPESWRSEVT 215

  Fly   309 HHDKLVYIYTSGTTGLPKAAVITHSRYFFIAAGIHYTLGFKDQDVFYTPLPLYHTAGGVMSMGQA 373
            .....|||||||||||||||.|.|.|.:: ...:....|.|..||.||.:||||:|..::.:...
  Rat   216 FTTPAVYIYTSGTTGLPKAATINHHRLWY-GTSLALRSGIKAHDVIYTTMPLYHSAALMIGLHGC 279

  Fly   374 LLFGSTVVIRKKFSASGYFSDCARFQCTVGQYIGEMARYILATPSAPHDRNHQVRMVFGNGLRPQ 438
            ::.|:|..:|.|||||.::.||.::..||.|||||:.||:..||..|:||:|:|::..|||||..
  Rat   280 IVVGATFALRSKFSASQFWDDCRKYNATVIQYIGELLRYLCNTPQKPNDRDHKVKIALGNGLRGD 344

  Fly   439 IWPQFVERFGIRKVGEFYGATEGNANIMNNDSTVGAIGFISRILPQIYPISIIKADPHTGEPLRN 503
            :|.:|::|||...:.|||.:||||...||....:||:|..:.:..::....:||.|....||:|:
  Rat   345 VWREFIKRFGDIHIYEFYASTEGNIGFMNYPRKIGAVGRENYLQKKVVRHELIKYDVEKDEPVRD 409

  Fly   504 SQGLCERCEADEPGVFVGKIVRGNPCREFLGYVDQKA-SSKKVVHDVFSKGDMAFISGDLLVADE 567
            :.|.|.:....|.|:.:.||....|   |.||...|. :.||.:.|||.|||:.|.|||||:.|.
  Rat   410 ANGYCIKVPKGEVGLLICKITELTP---FFGYAGGKTQTEKKKLRDVFKKGDVYFNSGDLLMIDR 471

  Fly   568 RGYLYFKDRTGDTFRWKGENVSTSEVEAQLSNLAGY-KDVIVYGVSIPNTEGRAGMAAI-YDPTR 630
            ..::||.||.|||||||||||:|:|| |.:..|..: ::|.||||.:|..|||.|||:| .....
  Rat   472 ENFIYFHDRVGDTFRWKGENVATTEV-ADIVGLVDFVEEVNVYGVPVPGHEGRIGMASIKMKENY 535

  Fly   631 EVNVSQLGVELAKSLPNYARPQFLRFLRKIDLTGTFKLRKVELQQQGFNPEIIDDELFYA-QPDG 694
            |.|..:|...:::.||:|:||:|||....|::|||||.|||.|.::||||.:|.|.|::. ..:.
  Rat   536 EFNGKKLFQHISEYLPSYSRPRFLRIQDTIEITGTFKHRKVTLMEEGFNPSVIKDTLYFMDDAEK 600

  Fly   695 VYAPLTPSVYERIVRNELR 713
            .|.|:|..:|..|:...|:
  Rat   601 TYVPMTEDIYNAIIDKTLK 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp2	NP_995925.2	Adenylate forming domain, Class I superfamily	163..680	CDD:473059	213/533 (40%)
Slc27a2	NP_113924.2	hsFATP2a_ACSVL_like	74..610	CDD:341261	221/561 (39%)