DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fatp2 and acsbg2

DIOPT Version :9

Sequence 1:	NP_995925.2	Gene:	Fatp2 / 37657	FlyBaseID:	FBgn0265187	Length:	714	Species:	Drosophila melanogaster
Sequence 2:	NP_001119851.1	Gene:	acsbg2 / 335159	ZFINID:	ZDB-GENE-030131-7099	Length:	752	Species:	Danio rerio

Alignment Length:	705	Identity:	139/705 - (19%)
Similarity:	229/705 - (32%)	Gaps:	218/705 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 LNIGDIFESNVARQPDKLAI-VSESQQW---TFRQVNEHSNRVANVFHSHGYKKGDVVGLLLENR 199
            |.:..:|.|.|.|.....|: ..|.:||   |:.:..:.....|..|...|.::...||:|..|.
Zfish   117 LTVNQMFTSTVQRFGSYPALGWKEGEQWKTMTYSEYYKSCRTAAKSFLKLGLERYHGVGILGFNS 181

  Fly   200 AE-FVATWLGLSKIGVITPLINTNLRGASLQHSITVGQCTA---LIYGASFRSAVMDIAKDLPAH 260
            .| |:|....:...|....:..||...|.   ......|.|   ::........::.|...||..
Zfish   182 TEWFIADIAAILAGGFAVGIYTTNSPEAC---QYVAENCQANILVVENHKQLQKILQIQDKLPHL 243

  Fly   261 VGLYQFNDESNQE----VVASEGLSQGLAQ---QLNGLLETAAKDKVAAGASRADHHDKLVYIYT 318
            ..:.|:.||..::    ...:|.:..|..:   ||:.::.:...::..            ..|||
Zfish   244 KAIIQYKDELKEKKPNLYTWAEFMELGRDEPDTQLDDIISSQKPNQCC------------TLIYT 296

  Fly   319 SGTTGLPKAAVITHSR--YFFIAAGIHYTLGFKD--QDVFYTPLPLYHTAGGVMSMGQALLFGST 379
            |||||.||..:::|..  :..:|...|.:|...|  |:|..:.|||.|.|..::.:...:..|..
Zfish   297 SGTTGQPKGVMLSHDNLTWTAVATSQHVSLNDADKLQEVVVSYLPLSHIAAQMIDIWLPMKAGGV 361

  Fly   380 VVIRKKFSASGYFSDCARFQCTVGQYIGEMARYILATPSAPHDRNHQVRMVFGNGLRPQIWPQFV 444
            ....:..:..|..::..|                            ::|.....|: |::|.:..
Zfish   362 TYFAQPDALKGSLANTLR----------------------------EIRPTAFLGV-PRVWEKMQ 397

  Fly   445 ERFGI---------RKVGEFYG--ATEGNANIMNNDSTVGAIGFISRILPQIYPISIIKADPHTG 498
            |:...         |||..:..  ..:.|.|.|.       :|..||     .|::...|.....
Zfish   398 EKMKSIGAKSSTVRRKVASWAKDVGLQTNLNKME-------LGSNSR-----KPLNYRLAKHLVF 450

  Fly   499 EPLRNSQGL--CERC-----------------------------EADEPGVFV----------GK 522
            ..:|.:.||  |.||                             |:..|....          ||
Zfish   451 RKVRKALGLDRCTRCYTGAAPITKDTLEFFLSLDIPLFELYGMSESSGPHTITQANAFRLTSCGK 515

  Fly   523 IVRG------NPCRE------------FLGYVDQKASSKKVVHDVFSKGDMAFISGDLLVADERG 569
            ::.|      ||..|            |:||::....:::.:.   ::|.:.  ||||...||..
Zfish   516 VIPGCKTKLSNPDDEKNGEICFWGRHVFMGYLNMPDKTEEALD---AEGWLH--SGDLGKLDENN 575

  Fly   570 YLYFKDRTGD-TFRWKGENVSTSEVEAQ--------------------LSNLAGYKDVIVYGVSI 613
            :|:...|..: .....|||:....:|..                    ||.|...|..|.....:
Zfish   576 FLFITGRIKELIITAGGENIPPVPIEDAVKEAIPLISNAMLIGDKRKFLSMLLTVKCQINGETGV 640

  Fly   614 PNTE--------------------------GRAGMAAIYDPTREVNVSQLGVELAKSLPNYARPQ 652
            |..|                          .||..|||.|....||        .|:..|..|.|
Zfish   641 PEDELTPEAVEFCRKLGSSCTRVTEIAGGRDRAVQAAIQDGINRVN--------EKATSNAQRIQ 697

  Fly   653 FLRFLRKI------DLTGTFKLRKVELQQQGFNPEIIDDELFYAQPDGVYAPLTP 701
            ....|.:.      :|..|.||::..:.:. :..:|   |.||.:   |..|:||
Zfish   698 KWTVLDQDFSIPGGELGPTMKLKRPVVMKM-YKEQI---ESFYKE---VVTPVTP 745

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp2	NP_995925.2	PRK08279	115..714	CDD:236217	139/705 (20%)
Fatp2	NP_995925.2	AFD_class_I	163..680	CDD:302604	124/657 (19%)
acsbg2	NP_001119851.1	FAA1	118..738	CDD:223953	134/692 (19%)
acsbg2	NP_001119851.1	ACSBG_like	139..736	CDD:213299	127/669 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583019
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930