Protein Alignment Fatp2 and acsl4b

DIOPT Version :10

• Sequence 1: NP_995925.2
• Gene: Fatp2 / 37657
• FlyBaseID: FBgn0265187
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_001093209.1
• Gene: acsl4b / 334561
• ZFINID: ZDB-GENE-030131-6493
• Length: 671
• Species: Danio rerio
• Alignment Length: 675
• Identity: 151/675 - (22%)
• Similarity: 235/675 - (34%)
• Gaps: 184/675 - (27%)

  Fly   131 IKRQERKNLNIGDIFESNVARQPDKLAIVSESQQW-TFRQVNEHSNRVANVFHSHGYKKGDVVGL 194
            :..:|.|..| |.||:.          :|..:..| ::..|::......:...:.|.|....:.:
Zfish    62 LSEEEEKQPN-GKIFKK----------LVLGNYSWMSYEAVDQAVESFGSGLAALGQKPRQTIAI 115

  Fly   195 LLENRAEFV-----------------------ATWLGLSKIGVI-----TPLINTNLRG-----A 226
            ..|.|||::                       |...||::.|..     |.|:.:.|:.     :
Zfish   116 FCETRAEWMIAAQACFRRNYPLVTLYATLGEDAVAYGLNQCGATHLITSTELLQSKLKNVLFAVS 180

  Fly   227 SLQHSITVGQCTALIYGASFRSAVMDIAKDLPAHVGLYQFNDESNQEVVASEGLSQGLAQQLNGL 291
            .|||.|.||  :..::.|       |..:.|..|         |.|||.
Zfish   181 GLQHVIYVG--SGEVHQA-------DYPQSLIIH---------SMQEVT---------------- 211

  Fly   292 LETAAK-DKVAAGASRADHHDKLVYIYTSGTTGLPKAAVITHSRYFFIAAGIHYTL-GFKDQDVF 354
             |..|| :.::....|....|..|.:||||:||.||...:.||......||....: |...||..
Zfish   212 -ELGAKPENLSVEYERPSASDLAVVMYTSGSTGNPKGVKMQHSNLIAGMAGQCQRIPGLGSQDTI 275

  Fly   355 YTPLPLYH----TAG-GVMSMGQALLFGS--TVVIRKKFSASGYFSDCARFQCT----------- 401
            .:.|||.|    ||. ..:|.|..|.:.|  |:..:......|...||:..:.|
Zfish   276 VSYLPLAHVLELTAEISCLSHGCRLGYSSPHTLTDQSSKIKKGSKGDCSVLKPTLIAAVPEIMDR 340

  Fly   402 ----VGQYIGEMA-----------RYILATPSAPHDRN-------HQVRMVFGNGLRPQI----- 439
                |...:.||:           .|.|...|...|..       .||.::.|..:|..:
Zfish   341 ICKNVNGKLQEMSVIKRTLFKLGFDYKLQQVSKGADSPMCDMLFFKQVNVLLGGCVRRMLSGGAP 405

  Fly   440 WPQFVERF---GIRKVGEFYGATE--GNANIM-NNDSTVGAIGFISRILPQIYPISIIKADPHTG 498
            .....:||   ....:...||.||  |...|. ::|.:.|.:|     .|.|.....::..|..|
Zfish   406 LSASTQRFMNVCFCPIAVGYGLTETCGAGTISDSSDYSTGRVG-----APLICSEIKLRDWPEGG 465

  Fly   499 EPLRNSQGLCERCEADEPGVFVGKIVRGNPCREFLGYVDQKASSKKVVHDVFSKGDMAFISGDLL 563
               ..||        |:|.. .|:|:.|.| ...:||...:...:.....|...|...|.:||:.
Zfish   466 ---YTSQ--------DKPHP-RGEILIGGP-NVAMGYYGSEGEGQNDNFWVDEAGQRWFSTGDIG 517

  Fly   564 VADERGYLYFKDRTGDTFRWK-GENVSTSEVEAQLSNLAGYKDVIVYGVS---------IPNTEG 618
            .....|.|...||..|..:.: ||.||..:|||.:.|.....::.||..|         :||.:.
Zfish   518 EVHPDGCLEIVDRKKDLVKLQAGEYVSLGKVEAAMKNSPLIDNICVYASSDQNYVISFVVPNQKN 582

  Fly   619 ------RAGMAAIYD-----PTREVNVSQLGVELA--KSLPNYARPQFLRFLRKI------DLTG 664
                  ::|:...:|     ...|..|.::..|:|  ..|..:..||.:|...:.      .:|.
Zfish   583 LTELAKKSGIDGEWDDICNHTMMEEEVLKVIKEIAVTSKLERFEVPQKIRLSSEPWTPETGLVTD 647

  Fly   665 TFKLRKVELQQQGFNPEIIDDELFY 689
            .|||::.||:    |..:.|.|..|
Zfish   648 AFKLKRKELK----NHYMKDIERLY 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp2	NP_995925.2	Adenylate forming domain, Class I superfamily	163..680	CDD:473059	140/632 (22%)
acsl4b	NP_001093209.1	Adenylate forming domain, Class I superfamily	81..656	CDD:473059	138/627 (22%)
		PRK04319	<140..>248	CDD:235279	35/142 (25%)