Protein Alignment Fatp2 and SLC27A6

DIOPT Version :9

• Sequence 1: NP_995925.2
• Gene: Fatp2 / 37657
• FlyBaseID: FBgn0265187
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_001017372.1
• Gene: SLC27A6 / 28965
• HGNCID: 11000
• Length: 619
• Species: Homo sapiens
• Alignment Length: 622
• Identity: 226/622 - (36%)
• Similarity: 346/622 - (55%)
• Gaps: 49/622 - (7%)

  Fly   106 WFYIAAVTTPRDTVALFAYIRVLLFIKRQERKN--LNIGDIFESNVARQPDKLAIVSESQQWTFR 168
            ||.:..|.             :::.:|:.|::.  :.:.|.|.|:..|||.|..|:.|...:|::
Human    32 WFVLKVVL-------------IIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEGDIYTYQ 83

  Fly   169 QVNEHSNRVANVFHSH-GYKKGDVVGLLLENRAEFVATWLGLSKIGVITPLINTNLRGASLQHSI 232
            .|::.|:|||:||.:| ..||||.|.||:.|..:||..|.||:|:|.:...:|||:|..||.:.|
Human    84 DVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCI 148

  Fly   233 TVGQCTALIYGASFRSAVMDIAKDLPAHVGLYQFNDESNQEVVASEGLSQGLAQQLNGLLETAAK 297
            ......||:.||.....|.:|...|..::.::...|...|.|::           |...|.|:..
Human   149 RACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSVPQGVIS-----------LKEKLSTSPD 202

  Fly   298 DKVAAGASRADHH------DKLVYIYTSGTTGLPKAAVITHSRYFFIAAGIHYTLGFKDQDVFYT 356
            :.|.     ..||      ...:||:|||||||||||||:..: ....:.:.:..|....|:.|.
Human   203 EPVP-----RSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ-VLRGSAVLWAFGCTAHDIVYI 261

  Fly   357 PLPLYHTAGGVMSMGQALLFGSTVVIRKKFSASGYFSDCARFQCTVGQYIGEMARYILATPSAPH 421
            .|||||::..::.:...:..|:|.|::||||||.::|||.::..||.|||||:.||:........
Human   262 TLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREG 326

  Fly   422 DRNHQVRMVFGNGLRPQIWPQFVERFGIRKVGEFYGATEGNANIMNNDSTVGAIGFISRILPQIY 486
            :::|:||:..|||:|..:|.:|::|||..||.|.|.|||.:.:.||....:||||..:.....:.
Human   327 EKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGAIGRTNLFYKLLS 391

  Fly   487 PISIIKADPHTGEPLRNSQGLCERCEADEPGVFVGKIVRGNPCREFLGYV-DQKASSKKVVHDVF 550
            ...:||.|....||:||.||.|...:..|||:.:.::...||   |.||. ..|.:..|::.|||
Human   392 TFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNP---FFGYAGPYKHTKDKLLCDVF 453

  Fly   551 SKGDMAFISGDLLVADERGYLYFKDRTGDTFRWKGENVSTSEVEAQLSNLAGYKDVIVYGVSIPN 615
            .|||:...:|||:|.|:..:|||.||||||||||||||:|:||...:..|...::..||||:|..
Human   454 KKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISG 518

  Fly   616 TEGRAGMAA-IYDPTREVNVSQLGVELAKSLPNYARPQFLRFLRKIDLTGTFKLRKVELQQQGFN 679
            .|||||||: |..|...:::.::..::...||.||.|:|||...|::.||||||.|.:|.:.|||
Human   519 YEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFN 583

  Fly   680 PEIIDDELFYAQPDGV---YAPLTPSVYERIVRNELR 713
            |..|.:.|::.  |.:   |..||..:|::|:..|::
Human   584 PLKISEPLYFM--DNLKKSYVLLTRELYDQIMLGEIK 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp2	NP_995925.2	PRK08279	115..714	CDD:236217	223/613 (36%)
		AFD_class_I	163..680	CDD:302604	201/525 (38%)
SLC27A6	NP_001017372.1	PRK08279	16..619	CDD:236217	226/622 (36%)
		hsFATP2a_ACSVL_like	77..609	CDD:213304	209/553 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149034
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000388
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100576
Panther	1	1.100	-	-	O	PTHR43107
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2110
SonicParanoid	1	1.000	-	-		X222
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.870