Protein Alignment Fatp2 and Slc27a5

DIOPT Version :10

• Sequence 1: NP_995925.2
• Gene: Fatp2 / 37657
• FlyBaseID: FBgn0265187
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_033538.2
• Gene: Slc27a5 / 26459
• MGIID: 1347100
• Length: 689
• Species: Mus musculus
• Alignment Length: 698
• Identity: 239/698 - (34%)
• Similarity: 354/698 - (50%)
• Gaps: 77/698 - (11%)

  Fly    51 KPPAKSNFRRYLQWILA-PVLTAISGLILYYQGPW------YGVATLYAALISILL---VRPGWR 105
            :||..:.....|:|.|. |....:.||.|..: ||      :.::.:.|||...||   ..||.|
Mouse    21 QPPWPAAMALALRWFLGDPTCLVLLGLALLGR-PWISSWMPHWLSLVGAALTLFLLPLQPPPGLR 84

  Fly   106 WFYIAAVTTPRDTVALFAYIRVLLFIKRQERKNLN------IGDIFESNVARQPDKLAIV---SE 161
            |.:       :|....|.    :||...:.|:.||      ..|..|......||::|:|   ||
Mouse    85 WLH-------KDVAFTFK----MLFYGLKFRRRLNKHPPETFVDALERQALAWPDRVALVCTGSE 138

  Fly   162 SQQWTFRQVNEHSNRVANVFHSHGYKKGDVVGLLLENRAEFVA-------------TWLGLSKIG 213
            ....|..|::..|.:.|.|.      |..:...:::|..:..|             .:|||:|:|
Mouse   139 GSSITNSQLDARSCQAAWVL------KAKLKDAVIQNTRDAAAILVLPSKTISALSVFLGLAKLG 197

  Fly   214 VITPLINTNLRGASLQHSITVGQCTALIYGASFRSAVMDI-AKDLPAHVGLYQFNDESNQEVVAS 277
            .....||.:.||..|.||:.....:.||.....:..:.:: .|.|..::..:.....|....|.:
Mouse   198 CPVAWINPHSRGMPLLHSVRSSGASVLIVDPDLQENLEEVLPKLLAENIHCFYLGHSSPTPGVEA 262

  Fly   278 EGLSQGLAQQLNGLLETAAKDKVAAGASRADHHDK--LVYIYTSGTTGLPKAAVITHSRYFFIAA 340
            .|.|          |:.|..|.|.| :.||....|  .::|:|||||||||.|:::|.|...::.
Mouse   263 LGAS----------LDAAPSDPVPA-SLRATIKWKSPAIFIFTSGTTGLPKPAILSHERVIQVSN 316

  Fly   341 GIHYTLGFKDQDVFYTPLPLYHTAGGVMSMGQALLFGSTVVIRKKFSASGYFSDCARFQCTVGQY 405
            .:.: .|.:..||.|..||||||.|.|:.....|..|:|.|:..|||||.::::|.:...||..|
Mouse   317 VLSF-CGCRADDVVYDVLPLYHTIGLVLGFLGCLQVGATCVLAPKFSASRFWAECRQHGVTVILY 380

  Fly   406 IGEMARYILATPSAPHDRNHQVRMVFGNGLRPQIWPQFVERFGIRKVGEFYGATEGNANIMNNDS 470
            :||:.||:...|..|.|:.|.||:..|||||..:|..|.:|||..::.||||:||||..:||...
Mouse   381 VGEILRYLCNVPEQPEDKIHTVRLAMGNGLRANVWKNFQQRFGPIRIWEFYGSTEGNVGLMNYVG 445

  Fly   471 TVGAIGFISRILPQIYPISIIKADPHTGEPLRNSQGLCERCEADEPGVFVGKIVRGNPCREFLGY 535
            ..||:|..|.||..:.|..:::.|..|.||||:.||.|...|..:||:.:.|:.:..|   ||||
Mouse   446 HCGAVGRTSCILRMLTPFELVQFDIETAEPLRDKQGFCIPVEPGKPGLLLTKVRKNQP---FLGY 507

  Fly   536 VDQKA-SSKKVVHDVFSKGDMAFISGDLLVADERGYLYFKDRTGDTFRWKGENVSTSEVEAQLSN 599
            ...:| |::|:|.:|...||:.|.:||:|..|:.|:.||:||.|||||||||||||.|||..||:
Mouse   508 RGSQAESNRKLVANVRRVGDLYFNTGDVLTLDQEGFFYFQDRLGDTFRWKGENVSTGEVECVLSS 572

  Fly   600 LAGYKDVIVYGVSIPNTEGRAGMAAI-YDPTREVNVSQLGVELAKSLPNYARPQFLRFLRKIDLT 663
            |...::|.||||.:|..||:.||||: ..|.:..:..:|...:...||.||.|.|:|....:::|
Mouse   573 LDFLEEVNVYGVPVPGCEGKVGMAAVKLAPGKTFDGQKLYQHVRSWLPAYATPHFIRIQDSLEIT 637

  Fly   664 GTFKLRKVELQQQGFNPEIIDDELFY----AQPDGVYAPLTPSVYERI 707
            .|:||.|..|.::||:..||.|.|:.    ||   .:..|.|.||:.:
Mouse   638 NTYKLVKSRLVREGFDVGIIADPLYILDNKAQ---TFRSLMPDVYQAV 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp2	NP_995925.2	Adenylate forming domain, Class I superfamily	163..680	CDD:473059	194/534 (36%)
Slc27a5	NP_033538.2	hsFATP2a_ACSVL_like	138..679	CDD:341261	203/564 (36%)